| L. CampanaCentre-forward |  New England Revolution | 🇪🇨Ecuador | 26 | 2 | 1 | 0 | 6.3 | 4▼84.4% | 33▼13.6% |
| D. PereiraCentral midfielder |  CF Montreal | 🇻🇪Venezuela | 26 | 15 | 0 | 1 | 6.2 | 5▼82.3%↩ | 33▼17.5%↩ |
| T. OstrákAttacking midfielder |  St. Louis City | 🇨🇿Czechia | 26 | 4 | 1 | 0 | 6.3 | 4▼79.2% | 33▼1.2% |
| M. SuleymanovCentre-forward |  Sporting Kansas City | 🇷🇺Russia | 26 | 21 | 1 | 1 | 6.2 | 12▼35% | 33▼8% |
| J. MaherCentre-back |  Nashville SC | 🇺🇸USA | 26 | 10 | 0 | 0 | 6.3 | 17▼9.6% | 34▼15.2% |
| I. MurphyCentre-back |  San Diego | 🇺🇸USA | 26 | 8 | 0 | 0 | 6.4 | 18▲118.1%↩ | 34▲2.4%↩ |
| A. JabbariWinger |  FC Cincinnati | 🇲🇦Morocco | 26 | 22 | 1 | 2 | 6.5 | 13 | 34▲14.8% |
| J. SandsCentre-back |  New York City FC | 🇺🇸USA | 26 | 10 | 1 | 0 | 8.3 | 9▼68.6%↩ | 35▼44.7%↩ |
| C. dos SantosGoalkeeper | San Diego | 🇺🇸USA | 26 | 11 | 0 | 0 | 6.7 | 12▼60% | 35▼16.5% |
| J. ShaffelburgWinger |  Los Angeles FC | 🇨🇦Canada | 26 | 15 | 0 | 3 | 6.7 | 9▼50.9%↩ | 35▼3%↩ |
| J. Sery LarsenCentre-back |  Philadelphia Union | 🇩🇰Denmark | 26 | 12 | 1 | 0 | 7.9 | 14▲33.6%↩ | 35▼3.3%↩ |
| M. FarsiFull-back |  Columbus Crew | 🇨🇦Canada | 26 | 14 | 1 | 3 | 7.3 | 8▼58.5% | 37▲1.1% |
| P. QuintonFull-back |  Real Salt Lake | 🇺🇸USA | 26 | 19 | 0 | 1 | 6.9 | 9▲16.9% | 37▲12.3% |
| E. EneliCentral midfielder | Real Salt Lake | 🇺🇸USA | 26 | 29 | 0 | 1 | 7.1 | 23▼37.1% | 38▼15.7% |
| Guilherme BiroCentre-back |  Austin | 🇧🇷Brazil | 26 | 22 | 3 | 1 | 7.3 | 21▼34% | 38▼7.8% |
| MicaelCentre-back |  Inter Miami | 🇧🇷Brazil | 26 | 17 | 1 | 0 | 10.3 | 26▲5.8%↩ | 38▼33.9%↩ |
| S. MorenoWinger |  FC Dallas | 🇨🇴Colombia | 26 | 20 | 3 | 2 | 7.2 | 18▼22.4%↩ | 38±0% |
| B. KikanovicFull-back |  San Jose Earthquakes | 🇺🇸USA | 26 | 20 | 0 | 0 | 9.5 | 24 | 39▲27.6% |
| Marco PasalicWinger |  Orlando City SC | 🇭🇷Croatia | 26 | 17 | 2 | 0 | 6.9 | 12▼74.3% | 39▼9.6% |
| C. HarrisWinger | Sporting Kansas City | 🏴England | 26 | 23 | 3 | 3 | 8.9 | 29▲47.7%↩ | 39▲10.7%↩ |
| J. SanabriaCentral midfielder | Real Salt Lake | 🇺🇾Uruguay | 26 | 21 | 1 | 4 | 12.6 | 39▲132.1%↩ | 39▼10.3%↩ |
| Bryan Josías Ramírez LeónDefensive midfielder | FC Cincinnati | 🇪🇨Ecuador | 26 | 22 | 0 | 3 | 11.1 | 33 | 39 |
| M. MaloneWinger |  Minnesota United FC | 🇩🇪Germany | 26 | 3 | 0 | 0 | 5.4 | 17±0% | 40▼7.5%↩ |
| J. SargentCentre-forward |  Toronto FC | 🇺🇸USA | 26 | 18 | 7 | 2 | 12.7 | 37▲40.1%↩ | 40▼32.4%↩ |
| B. OjedaCentral midfielder | Orlando City SC | 🇵🇾Paraguay | 26 | 18 | 1 | 2 | 12.1 | 34▲31.4%↩ | 40▲7.4%↩ |
| C. WallemCentral midfielder | St. Louis City | 🇳🇴Norway | 26 | 21 | 1 | 3 | 12.3 | 35▲16.1% | 40▲7.7% |
| C. DurkinDefensive midfielder | St. Louis City | 🇺🇸USA | 26 | 22 | 2 | 0 | 12.9 | 39▲186.1% | 40▲24.7% |
| Alonso CoelloDefensive midfielder | Toronto FC | 🇪🇸Spain | 26 | 25 | 0 | 3 | 11.8 | 39▲35.6% | 40▲5.2% |
| O. UrhoghideCentre-back | FC Dallas | 🇳🇱Netherlands | 26 | 20 | 1 | 1 | 8.3 | 25▼5.7% | 41▲5.2% |
| F. TorresAttacking midfielder | Austin | 🇺🇾Uruguay | 26 | 25 | 4 | 6 | 12.3 | 35▲23.8%↩ | 41▼35.6%↩ |
| L. PetrassoFull-back | CF Montreal | 🇨🇦Canada | 26 | 23 | 0 | 3 | 7.9 | 19▲27.8% | 41▼1.9% |
| S. ZawadzkiCentral midfielder | Columbus Crew | 🇺🇸USA | 26 | 25 | 0 | 0 | 7.7 | 22▼29.6% | 41▲4.8% |
| T. TotlandFull-back | St. Louis City | 🇳🇴Norway | 26 | 21 | 2 | 4 | 7.9 | 15▲21.4% | 41▲27.6% |
| A. MarkanichFull-back | Minnesota United FC | 🇺🇸USA | 26 | 25 | 7 | 2 | 9.4 | 32▼9.7% | 41▲1.5% |
| N. CaliskanDefensive midfielder | Real Salt Lake | 🇩🇪Germany | 26 | 24 | 1 | 3 | 12.9 | 43▲65.3% | 41▲11% |
| W. SandsCentre-back | New England Revolution | 🇺🇸USA | 26 | 25 | 1 | 0 | 8.1 | 28▲217% | 42▲27.3% |
| L. GavranGoalkeeper | Toronto FC | 🇨🇦Canada | 26 | 25 | 1 | 0 | 7.8 | 5▲73.3% | 42▲35.6% |
| M. LongstaffCentral midfielder | CF Montreal | 🏴England | 26 | 24 | 2 | 3 | 11.2 | 37▲102.2%↩ | 42▲14.1%↩ |
| A. YusufCentral midfielder | New England Revolution | 🇳🇬Nigeria | 26 | 24 | 5 | 1 | 13 | 52▲40.9% | 42▲1.7% |
| K. YeboahCentre-forward | Minnesota United FC | 🇮🇹Italy | 26 | 24 | 13 | 2 | 12.9 | 54▲87.8% | 42▲5% |
| O. BoudaCentral midfielder | San Jose Earthquakes | 🇧🇫Burkina Faso | 26 | 25 | 6 | 1 | 13.4 | 45▲206.1% | 42▲18.2% |
| D. PolvaraCentre-back | St. Louis City | 🇺🇸USA | 26 | 25 | 1 | 0 | 9.2 | 31▲130.6%↩ | 42▲17.2%↩ |
| D. MunieCentre-back | San Jose Earthquakes | 🇺🇸USA | 26 | 23 | 4 | 1 | 9 | 26▲56.4% | 42▲14.9% |
| D. Jean-JacquesCentral midfielder | Philadelphia Union | 🇭🇹Haiti | 26 | 24 | 4 | 1 | 13.3 | 51▲37.4% | 43▲8.4% |
| R. CelentanoGoalkeeper | FC Cincinnati | 🇺🇸USA | 26 | 23 | 0 | 0 | 7.5 | 3▼88.6% | 43▲3.9% |
| N. Fernández MercauWinger | New York City FC | 🇦🇷Argentina | 26 | 24 | 15 | 4 | 14.3 | 65▲244.1% | 45▲22.2% |
| S. RodríguezWinger | Columbus Crew | 🇺🇾Uruguay | 26 | 3 | 2 | 0 | 6.5 | 20±0% | 52▼13.4%↩ |
| I. SadiqCentre-forward | Colorado Rapids | 🇬🇭Ghana | 26 | 20 | 2 | 0 | 10.5 | 9▼69.9%↩ | 53▼20.3%↩ |
| Y. DiabyWinger |  Vancouver Whitecaps | 🇬🇳Guinea | 26 | 3 | 0 | 0 | 5.8 | 38±0% | 55±0% |
| Rui ModestoCentral midfielder | Vancouver Whitecaps | 🇦🇴Angola | 26 | 1 | 0 | 0 | 5.8 | 2▼60%↩ | 58▲13.6%↩ |
| L. FosterCentre-forward |  Houston Dynamo | 🇿🇦South Africa | 26 | 26 | 3 | 2 | 13.6 | 19▲8.5%↩ | 74▲10%↩ |
| J. Adebayo-SmithCentre-forward | Minnesota United FC | 🇺🇸USA | 25 | 6 | 0 | 0 | 5 | 0 | 27▼22.7% |
| Jeong Ho-YeonDefensive midfielder | Minnesota United FC | 🇰🇷Korea Republic | 25 | 4 | 0 | 0 | 5.9 | 2▼78.7%↩ | 32▼38.8%↩ |
| D. OdleGoalkeeper | New York Red Bulls | 🇺🇸USA | 25 | 0 | 0 | 0 | 6 | 0 | 32 |
| F. AmayaCentral midfielder | CF Montreal | 🇺🇸USA | 25 | 1 | 0 | 0 | 6 | 0▼100%↩ | 32▼14.7%↩ |
| MusuCentre-forward | New York City FC | 🇮🇹Italy | 25 | 1 | 0 | 0 | 6 | 0 | 32 |
| Puree UpdullohCentral midfielder | New England Revolution | 🇹🇭Thailand | 25 | 1 | 0 | 0 | 6 | 0 | 32 |
| B. DukeCentral midfielder | San Diego | 🇺🇸USA | 25 | 5 | 0 | 0 | 6 | 1▼93%↩ | 32▼11.5%↩ |
| L. GiacconeCentral midfielder | Columbus Crew | 🇦🇷Argentina | 25 | 5 | 0 | 0 | 6.1 | 1▼96.3%↩ | 32▼32.3%↩ |
| M. MosqueraCentre-back | Sporting Kansas City | 🇨🇴Colombia | 25 | 7 | 0 | 0 | 6.2 | 9▼44.8%↩ | 33▼29.5%↩ |
| B. CeballosCentre-back | CF Montreal | 🇨🇴Colombia | 25 | 9 | 2 | 0 | 6.4 | 2▼95.8%↩ | 33▼23.5%↩ |
| Geovane JesusCentre-back | FC Dallas | 🇧🇷Brazil | 25 | 0 | 0 | 0 | 6.2 | 0 | 33 |
| C. HolstadCentral midfielder | FC Dallas | 🏳️ | 25 | 2 | 0 | 0 | 6.2 | 0 | 33 |
| Joran GerbetCentral midfielder | Orlando City SC | 🇫🇷France | 25 | 6 | 0 | 1 | 7 | 2▼83.6% | 33▼9.5% |
| Edward BerumenCentre-back | Los Angeles FC | 🇺🇸USA | 25 | 0 | 0 | 0 | 6.1 | 0 | 33 |
| Matheus PereiraCentre-back | Toronto FC | 🇧🇷Brazil | 25 | 8 | 0 | 0 | 6.7 | 2▼80.8%↩ | 34▼35.3%↩ |
| Cesar RuvalcabaCentre-back | Columbus Crew | 🇺🇸USA | 25 | 6 | 0 | 0 | 6.4 | 7▲73.7% | 34▼2% |
| T. RomeroGoalkeeper | New York City FC | 🇸🇻El Salvador | 25 | 4 | 0 | 0 | 6.5 | 5▲200%↩ | 35▼1.4%↩ |
| J. PulskampGoalkeeper | Sporting Kansas City | 🇺🇸USA | 25 | 9 | 0 | 0 | 6.5 | 0▼100% | 35▼17.9% |
| N. AdimabuaWinger | San Jose Earthquakes | 🏳️ | 25 | 2 | 0 | 1 | 6.7 | 3 | 35 |
| J. ReidDefensive midfielder | Sporting Kansas City | 🇺🇸USA | 25 | 18 | 0 | 0 | 6.8 | 13▲131%↩ | 36▲8.8%↩ |
| D. McGuireCentre-forward | Houston Dynamo | 🇺🇸USA | 25 | 14 | 2 | 0 | 7 | 0▼100%↩ | 36▼3.7%↩ |
| A. MekvabishviliCentral midfielder |  Chicago Fire | 🇬🇪Georgia | 25 | 33 | 3 | 7 | 11.8 | 36 | 37 |
| S. AfrifaWinger | Sporting Kansas City | 🇨🇦Canada | 25 | 20 | 3 | 1 | 6.8 | 16 | 37▲18.4% |
| R. VoloderCentre-back |  New York Red Bulls | 🇩🇪Germany | 25 | 8 | 0 | 0 | 6.8 | 9▼33.6%↩ | 37▲0.8%↩ |
| B. BenderDefensive midfielder | Philadelphia Union | 🇺🇸USA | 25 | 8 | 1 | 0 | 6.9 | 13▲1333.3% | 37▲10.4% |
| Wyatt MeyerCentre-back | Sporting Kansas City | 🇺🇸USA | 25 | 18 | 0 | 0 | 7.5 | 13▲746.7%↩ | 38▲13%↩ |
| A. PereaCentral midfielder | New York City FC | 🇺🇸USA | 25 | 15 | 1 | 1 | 10.5 | 20▼30.8% | 38▼7.1% |
| J. SiroisGoalkeeper | FC Dallas | 🇨🇦Canada | 25 | 10 | 0 | 0 | 8.2 | 6▲64.1%↩ | 39▼5.6%↩ |
| G. LujánCentre-back | Inter Miami | 🇦🇷Argentina | 25 | 16 | 1 | 0 | 7.3 | 17▲16.3% | 39±0% |
| N. DefreitasGoalkeeper |  Colorado Rapids | 🇩🇰Denmark | 25 | 14 | 0 | 0 | 7.5 | 18▲376.3% | 40▲11% |
| A. ZarouryWinger | Columbus Crew | 🇲🇦Morocco | 25 | 29 | 4 | 2 | 7.6 | 21▲22%↩ | 40▼46.4%↩ |
| P. de la VegaWinger |  Seattle Sounders | 🇦🇷Argentina | 25 | 26 | 4 | 4 | 8.9 | 29▲313% | 40▲6.7% |
| K. TrewinCentre-back | New York City FC | 🇦🇺Australia | 25 | 15 | 0 | 0 | 9.5 | 17▲59.6%↩ | 40▲130.6%↩ |
| T. SpicerWinger | Orlando City SC | 🇹🇹Trinidad and Tobago | 25 | 21 | 5 | 1 | 7.9 | 25▲33%↩ | 40▲1.8%↩ |
| E. TagsethDefensive midfielder | Nashville SC | 🇳🇴Norway | 25 | 20 | 1 | 0 | 9.2 | 24▼16% | 40▼5.2% |
| Michael CollodiGoalkeeper | FC Dallas | 🇺🇸USA | 25 | 13 | 0 | 0 | 7.6 | 5▲25% | 41▲11.5% |
| J. FerreiraAttacking midfielder | Seattle Sounders | 🇺🇸USA | 25 | 18 | 2 | 3 | 9 | 24▼16.7% | 41▼7% |
| Y. BrightDefensive midfielder | Inter Miami | 🇮🇹Italy | 25 | 21 | 0 | 0 | 10.2 | 27▲30.3% | 41▲10.2% |
| J. DíazCentre-back | Minnesota United FC | 🇨🇴Colombia | 25 | 23 | 0 | 1 | 8.2 | 28▲10.4% | 42▼3% |
| J. RosalesCentral midfielder | Austin | 🇭🇳Honduras | 25 | 24 | 1 | 4 | 12.6 | 39▲114.2%↩ | 42▲2.2%↩ |
| N. PalacioDefensive midfielder | Toronto FC | 🇨🇴Colombia | 25 | 32 | 0 | 1 | 8.8 | 28▲136.1%↩ | 42▲5%↩ |
| O. LarrazCentral midfielder | Vancouver Whitecaps | 🇺🇸USA | 25 | 19 | 0 | 3 | 10 | 24▼23.1%↩ | 43▲0.7%↩ |
| V. LoturiCentral midfielder | CF Montreal | 🇨🇦Canada | 25 | 24 | 1 | 1 | 10 | 32▲7% | 43▲1% |
| I. VassilevCentral midfielder | Philadelphia Union | 🇺🇸USA | 25 | 24 | 3 | 3 | 11 | 31▼7.8% | 43±0% |
| J. HaakDefensive midfielder |  Los Angeles Galaxy | 🇺🇸USA | 25 | 25 | 0 | 1 | 9.2 | 30▼27.5%↩ | 43▼3.6%↩ |
| J. ValienteAttacking midfielder | FC Dallas | 🇺🇾Uruguay | 25 | 23 | 2 | 8 | 10.8 | 31 | 44 |
| M. DugganCentre-back | Minnesota United FC | 🇩🇪Germany | 25 | 24 | 1 | 0 | 9.5 | 30▲85.8% | 44▲7.1% |
| J. RuvalcabaCentre-forward | New York Red Bulls | 🇲🇽Mexico | 25 | 24 | 7 | 0 | 10.9 | 36▲58%↩ | 44▼11.9%↩ |
| C. BassettAttacking midfielder |  Portland Timbers | 🇺🇸USA | 25 | 21 | 3 | 4 | 10.9 | 28▼3.4%↩ | 44▲1.8%↩ |
