| O. WolffWinger |  Austin | 🇺🇸USA | 21 | 7 | 8 | 11.5 | 41▲100.5% | 50▲15.6% |
| L. BombinoFull-back |  San Diego | 🇺🇸USA | 20 | 1 | 3 | 13 | 51 | 49 |
| S. BerhalterDefensive midfielder |  Vancouver Whitecaps | 🇺🇸USA | 25 | 4 | 10 | 15.2 | 59▲109.6% | 49▲13.5% |
| D. LunaAttacking midfielder |  Real Salt Lake | 🇺🇸USA | 22 | 9 | 3 | 12.2 | 41▲13.2% | 49±0% |
| I. FeingoldCentral midfielder |  New England Revolution | 🇮🇱Israel | 21 | 3 | 3 | 9.8 | 35 | 48 |
| Z. GozoAttacking midfielder | Real Salt Lake | 🇺🇸USA | 19 | 4 | 3 | 7.2 | 25 | 48▲31.9% |
| Marco PasalicCentral midfielder |  Orlando City SC | 🇭🇷Croatia | 25 | 12 | 5 | 14.9 | 57 | 48▼27.3%↩ |
| I. Toklomati GiornoCentre-forward |  Charlotte | 🇮🇱Israel | 21 | 12 | 3 | 11.1 | 39 | 48▲29.9% |
| J. McGlynnAttacking midfielder |  Houston Dynamo | 🇺🇸USA | 23 | 6 | 9 | 14.9 | 48▲68.7%↩ | 48▲2.1%↩ |
| AntonyAttacking midfielder |  Portland Timbers | 🇧🇷Brazil | 24 | 7 | 7 | 13 | 42▲42.2% | 48▲5.1% |
| K. DenkeyCentre-forward |  FC Cincinnati | 🇹🇬Togo | 25 | 26 | 1 | 14.8 | 57▲90%↩ | 47▼14%↩ |
| É. OcampoFull-back | Vancouver Whitecaps | 🇨🇴Colombia | 22 | 2 | 0 | 11.6 | 39▲3810% | 47▲30.4% |
| M. ArfstenDefensive midfielder |  Columbus Crew | 🇺🇸USA | 25 | 5 | 6 | 14.7 | 51▲91.8% | 47▲0.6% |
| P. MillerFull-back | New England Revolution | 🇺🇸USA | 18 | 2 | 2 | 6.9 | 29▲357.8% | 47▲17.9% |
| Beau LerouxCentral midfielder |  San Jose Earthquakes | 🇺🇸USA | 22 | 5 | 3 | 13.1 | 44 | 47 |
| C. BradyGoalkeeper |  Chicago Fire | 🇺🇸USA | 22 | 0 | 0 | 8.3 | 9▲87% | 47▲1.8% |
| F. SurmanCentre-back | Portland Timbers | 🇳🇿New Zealand | 22 | 0 | 0 | 8.4 | 28▲7000% | 46▲28.6% |
| Igor JesusDefensive midfielder |  Los Angeles FC | 🇧🇷Brazil | 23 | 0 | 1 | 8.9 | 29▲232.6%↩ | 46▼14.4%↩ |
| F. WestfieldCentral midfielder |  Philadelphia Union | 🇺🇸USA | 20 | 1 | 3 | 7.4 | 28 | 46 |
| D. SealyAttacking midfielder |  CF Montreal | 🇺🇸USA | 23 | 9 | 1 | 11.1 | 36▲600%↩ | 46▲18.8%↩ |
| J. HaakCentre-back |  New York City FC | 🇺🇸USA | 24 | 2 | 4 | 13.1 | 42▲323.2% | 46▲17.6% |
| T. JohnsonFull-back | Vancouver Whitecaps | 🇺🇸USA | 21 | 1 | 1 | 8.4 | 30 | 46 |
| C. dos SantosGoalkeeper | San Diego | 🇺🇸USA | 25 | 0 | 0 | 10.3 | 33 | 46▲27.9%↩ |
| David Pereira da CostaAttacking midfielder | Portland Timbers | 🇵🇹Portugal | 25 | 4 | 6 | 9.2 | 30▲1866.7%↩ | 46▼28.2%↩ |
| N. RomeroCentre-back |  Minnesota United FC | 🇦🇷Argentina | 22 | 0 | 5 | 8.1 | 26▼49.7%↩ | 46▼23.7%↩ |
| N. OrdazAttacking midfielder | Los Angeles FC | 🇸🇻El Salvador | 22 | 6 | 3 | 8.1 | 26▲401.9% | 46▲14.2% |
| Q. SullivanAttacking midfielder | Philadelphia Union | 🇺🇸USA | 22 | 2 | 7 | 8.9 | 30▼18.3% | 46▼3.8% |
| J. FerreiraAttacking midfielder |  Seattle Sounders | 🇺🇸USA | 25 | 4 | 6 | 9 | 29▲25.5%↩ | 46▲8.8%↩ |
| J. NelsonAttacking midfielder | Vancouver Whitecaps | 🇨🇦Canada | 23 | 2 | 5 | 8.5 | 22▲217.6%↩ | 45▲11%↩ |
| R. CelentanoGoalkeeper | FC Cincinnati | 🇺🇸USA | 25 | 0 | 0 | 8.5 | 14▼20.1% | 45▼4.6% |
| O. MakhanyaCentre-back | Philadelphia Union | 🇿🇦South Africa | 22 | 1 | 0 | 13.4 | 46 | 45 |
| C. BassettDefensive midfielder |  Colorado Rapids | 🇺🇸USA | 25 | 3 | 3 | 10.4 | 33▼12.3% | 45▼5.5% |
| J. LukićCentral midfielder | Philadelphia Union | 🇷🇸Serbia | 24 | 2 | 2 | 13 | 42 | 45▲3.7%↩ |
| D. MartínezCentre-forward | Los Angeles FC | 🇻🇪Venezuela | 20 | 3 | 5 | 7.2 | 20▲61.1% | 45▲6.1% |
| D. YapiAttacking midfielder | Colorado Rapids | 🇺🇸USA | 21 | 8 | 2 | 8.4 | 30▲217% | 45▲7.2% |
| O. ValakariCentral midfielder | San Diego | 🇫🇮Finland | 26 | 5 | 8 | 14 | 47▲221.9%↩ | 45▲30.5%↩ |
| T. SegoviaAttacking midfielder |  Inter Miami | 🇻🇪Venezuela | 23 | 9 | 4 | 10.1 | 32▲76.1%↩ | 45▼24.7%↩ |
| T. CorbeanuAttacking midfielder |  Toronto FC | 🇨🇦Canada | 24 | 6 | 2 | 8.8 | 28 | 45▼18.5%↩ |
| I. VassilevCentral midfielder | Philadelphia Union | 🇺🇸USA | 25 | 6 | 3 | 12 | 39▲45.1%↩ | 44▼1.1%↩ |
| L. LangoniCentral midfielder | New England Revolution | 🇦🇷Argentina | 24 | 2 | 2 | 8.3 | 25▲158.3%↩ | 44▼11.6%↩ |
| Gabriel PiraniWinger |  DC United | 🇧🇷Brazil | 24 | 7 | 3 | 10.2 | 33▲46.2% | 44▲5.5% |
| M. SofoWinger |  New York Red Bulls | 🇬🇭Ghana | 21 | 5 | 0 | 7.4 | 20 | 44▲21.8% |
| J. MosqueraFull-back | Portland Timbers | 🇨🇴Colombia | 23 | 1 | 2 | 8.3 | 15▼20.7% | 44▼5.8% |
| K. VargasAttacking midfielder | Charlotte | 🇨🇴Colombia | 24 | 6 | 3 | 8.3 | 26▼2.2% | 44▼7.2% |
| M. LabordaCentre-back | Vancouver Whitecaps | 🇺🇾Uruguay | 26 | 6 | 1 | 13.7 | 44▲86.9% | 44▲6% |
| S. OregelCentral midfielder | Chicago Fire | 🇺🇸USA | 21 | 0 | 0 | 7.4 | 12 | 44▲25.1% |
| PeglowCentral midfielder | DC United | 🇧🇷Brazil | 24 | 3 | 3 | 10.9 | 35▲330.9%↩ | 44▲27%↩ |
| D. AyalaDefensive midfielder | Portland Timbers | 🇦🇷Argentina | 24 | 2 | 1 | 12.2 | 39▲61.3% | 44▲7.4% |
| P. SchulteGoalkeeper | Columbus Crew | 🇺🇸USA | 25 | 0 | 0 | 8.2 | 9▼68.8% | 44▼6% |
| B. DamianiCentre-forward | Philadelphia Union | 🇺🇾Uruguay | 24 | 8 | 1 | 9 | 29 | 44 |
| T. GrayFull-back | New York City FC | 🇯🇲Jamaica | 23 | 0 | 0 | 10.4 | 33▲98.8% | 44▼2% |
| KaickCentral midfielder |  FC Dallas | 🇧🇷Brazil | 20 | 2 | 0 | 7.1 | 27 | 44 |
| Gabriel PecWinger |  Los Angeles Galaxy | 🇧🇷Brazil | 25 | 7 | 3 | 11 | 35▼49.2% | 44▼13.9% |
| O. LarrazDefensive midfielder | Colorado Rapids | 🇺🇸USA | 24 | 0 | 3 | 9.9 | 32▲5% | 43▼0.7% |
| M. DuahCentre-back | San Diego | 🇬🇭Ghana | 21 | 0 | 0 | 7.3 | 22 | 43 |
| G. ValenzuelaWinger | FC Cincinnati | 🇺🇸USA | 21 | 9 | 1 | 7.5 | 27▲152.8% | 43▲4.8% |
| J. RosalesFull-back | Minnesota United FC | 🇭🇳Honduras | 25 | 1 | 2 | 8.1 | 24▼46.3% | 43▼5.3% |
| O. VerhoevenCentre-back | San Diego | 🇺🇸USA | 20 | 0 | 0 | 6.9 | 15▲565.2%↩ | 43▲14%↩ |
| B. CeballosCentre-back | New England Revolution | 🇨🇴Colombia | 25 | 1 | 0 | 12.4 | 40▲1000%↩ | 43▲19.3%↩ |
| K. ThompsonCentre-back | Toronto FC | 🇨🇦Canada | 23 | 0 | 0 | 8.9 | 29▲235.3% | 43▲10.5% |
| N. AllenCentre-back | Inter Miami | 🇺🇸USA | 22 | 0 | 1 | 7.7 | 20▲106.1% | 43▲3.3% |
| K. KelsyCentre-forward | Portland Timbers | 🇻🇪Venezuela | 22 | 7 | 1 | 7.7 | 25▲31%↩ | 43▼3.8%↩ |
| D. EdelmanDefensive midfielder | New York Red Bulls | 🇺🇸USA | 23 | 1 | 0 | 8.1 | 24▲20.9% | 43▼6.9% |
| A. PereaDefensive midfielder | New York City FC | 🇺🇸USA | 25 | 3 | 2 | 11.7 | 38▲72.5% | 43▲4.4% |
| K. Kossa-RienziFull-back | Seattle Sounders | 🇺🇸USA | 24 | 3 | 2 | 8 | 19▲9300% | 43▲24.3% |
| L. FarringtonCentre-forward | FC Dallas | 🇺🇸USA | 24 | 5 | 3 | 8 | 24▲20.2% | 43▲1.9% |
| D. KerrCentre-forward | Toronto FC | 🇨🇦Canada | 23 | 5 | 0 | 8 | 25▲85.8% | 43▲6.7% |
| P. DelgadoWinger | FC Dallas | 🇪🇨Ecuador | 22 | 1 | 6 | 7.6 | 20▼15.9% | 43▲0.5% |
| Mateo SilvettiWinger | Inter Miami | 🇦🇷Argentina | 20 | 2 | 2 | 6.8 | 17▼24.3%↩ | 43▼16.6%↩ |
| H. SynchukAttacking midfielder | CF Montreal | 🇺🇦Ukraine | 20 | 1 | 0 | 6.8 | 9▲41%↩ | 43▲37.6%↩ |
| R. PrisoCentre-back | Vancouver Whitecaps | 🇨🇦Canada | 24 | 1 | 2 | 8 | 23▲367.3% | 43▲10.9% |
| J. Marshall-RuttyFull-back | Charlotte | 🇨🇦Canada | 22 | 0 | 2 | 7.9 | 27▲45.1%↩ | 43▲0.9%↩ |
| O. ValenciaDefensive midfielder | New York Red Bulls | 🇵🇦Panama | 22 | 0 | 5 | 7.6 | 26 | 43▲19.2% |
| N. HarrielFull-back | Philadelphia Union | 🇺🇸USA | 25 | 2 | 0 | 13.3 | 54▲72.7% | 43±0% |
| N. PierreCentre-forward | Vancouver Whitecaps | 🇺🇸USA | 21 | 1 | 0 | 7.2 | 4 | 43 |
| J. ForyFull-back | Portland Timbers | 🇨🇴Colombia | 24 | 0 | 2 | 8 | 24 | 43 |
| Rafael NavarroCentre-forward | Colorado Rapids | 🇧🇷Brazil | 26 | 12 | 3 | 13.3 | 48±0% | 43▼9% |
| E. TagsethCentral midfielder |  Nashville SC | 🇳🇴Norway | 25 | 0 | 2 | 9.2 | 30±0% | 43▼10.3%↩ |
| Felipe AndradeFull-back | Houston Dynamo | 🇧🇷Brazil | 24 | 4 | 1 | 11.1 | 36▲624.5%↩ | 43▼25%↩ |
| R. ElloumiCentre-forward | Vancouver Whitecaps | 🇨🇦Canada | 18 | 2 | 0 | 6 | 5 | 43 |
| J. BadwalAttacking midfielder | Vancouver Whitecaps | 🇨🇦Canada | 20 | 1 | 2 | 6.8 | 9 | 43 |
| P. StroudDefensive midfielder | New York Red Bulls | 🇺🇸USA | 24 | 0 | 3 | 8.5 | 27▲142.9% | 43▲8.7% |
| J. PulskampGoalkeeper |  Sporting Kansas City | 🇺🇸USA | 25 | 0 | 2 | 8 | 4▲168.7% | 43▲16.1% |
| E. MoralesCentre-back | CF Montreal | 🇧🇴Bolivia | 22 | 0 | 0 | 7.5 | 22▲2700%↩ | 42▲17.1%↩ |
| A. SmolyakovFull-back | Los Angeles FC | 🇺🇦Ukraine | 23 | 1 | 3 | 7.9 | 14▼10.1%↩ | 42▲7.3%↩ |
| J. DíazCentre-back | Minnesota United FC | 🇨🇴Colombia | 25 | 1 | 3 | 7.9 | 25▲139% | 42▲10.4% |
| J. FernándezWinger | New York City FC | 🇦🇷Argentina | 22 | 3 | 5 | 7.5 | 20▲94.1% | 42▲1% |
| N. TriantisCentral midfielder | Minnesota United FC | 🇦🇺Australia | 23 | 3 | 2 | 7.9 | 16▼57.9%↩ | 42▼23.6%↩ |
| V. LoturiDefensive midfielder | CF Montreal | 🇨🇦Canada | 25 | 2 | 0 | 9.4 | 30▲1410%↩ | 42▲12.6%↩ |
| T. HabrouneAttacking midfielder | Columbus Crew | 🇺🇸USA | 20 | 1 | 1 | 6.7 | 7▲722.2% | 42▲9.7% |
| D. TurgemanCentre-forward | New England Revolution | 🇮🇱Israel | 22 | 3 | 1 | 7.5 | 9 | 42 |
| P. YazbekCentral midfielder | Nashville SC | 🇦🇺Australia | 24 | 1 | 0 | 7.9 | 23▲231.9%↩ | 42▲6.3%↩ |
| C. ClarkWinger | CF Montreal | 🇺🇸USA | 23 | 0 | 4 | 7.9 | 13▲78.7%↩ | 42▲6.9%↩ |
| I. FrayFull-back | Inter Miami | 🇯🇲Jamaica | 23 | 1 | 3 | 7.9 | 17▲152.9% | 42▲1.7% |
| A. FortuneDefensive midfielder |  Atlanta United FC | 🇹🇹Trinidad and Tobago | 23 | 1 | 0 | 7.9 | 24▲24.9% | 42▼1.2% |
| L. PetrassoFull-back | CF Montreal | 🇨🇦Canada | 26 | 2 | 4 | 7.8 | 15 | 42▲22.9%↩ |
| D. BugajFull-back | CF Montreal | 🇵🇱Poland | 22 | 0 | 2 | 7.5 | 15▲2860% | 42▲15.7% |
| J. ShoreCentral midfielder | New York City FC | 🇺🇸USA | 19 | 1 | 0 | 6.3 | 19 | 42 |
| Jayden HibbertGoalkeeper | Atlanta United FC | 🇯🇲Jamaica | 22 | 0 | 0 | 7 | 3 | 42 |
| S. BrunellAttacking midfielder | Seattle Sounders | 🇺🇸USA | 19 | 2 | 0 | 6.3 | 11 | 42 |
