| N. ToloFull-back |  Seattle Sounders | 🇨🇲Cameroon | 29 | 1 | 2 | 4.1 | 24▼28.7% | 30▼16.4% |
| J. RagenCentre-back | Seattle Sounders | 🇺🇸USA | 27 | 2 | 1 | 7.4 | 24▼38.7% | 35▼20.7% |
| L. FarringtonWinger |  FC Dallas | 🇺🇸USA | 24 | 5 | 3 | 8 | 24▲16.7% | 43▲1.9% |
| Carlos CoronelGoalkeeper |  New York Red Bulls | 🇵🇾Paraguay | 29 | 0 | 0 | 4 | 24▲43% | 31▼15.4% |
| G. FloresCentre-back |  FC Cincinnati | 🇵🇾Paraguay | 23 | 0 | 0 | 7.8 | 24 | 41 |
| T. MüllerCentre-forward |  Vancouver Whitecaps | 🇩🇪Germany | 36 | 8 | 3 | 1 | 24▲29.8%↩ | 10▼48.5%↩ |
| Q. SullivanAttacking midfielder |  Philadelphia Union | 🇺🇸USA | 22 | 2 | 7 | 7.7 | 24▼36% | 44▼8.4% |
| J. PalaciosCentre-back |  Nashville SC | 🇨🇴Colombia | 32 | 2 | 0 | 2.3 | 23 | 18 |
| K. DuncanFull-back | New York Red Bulls | 🇺🇸USA | 28 | 0 | 3 | 4.3 | 23▲50% | 31▼11.1% |
| J. AtencioDefensive midfielder |  Colorado Rapids | 🇺🇸USA | 24 | 0 | 0 | 7.5 | 23▲56.1%↩ | 40▲2%↩ |
| D. YedlinFull-back | FC Cincinnati | 🇺🇸USA | 33 | 0 | 4 | 1.7 | 23±0% | 15▼33.6% |
| P. YazbekCentral midfielder | Nashville SC | 🇦🇺Australia | 24 | 1 | 0 | 7.9 | 23▲231.9%↩ | 42▲6.3%↩ |
| J. BondGoalkeeper |  Houston Dynamo | 🏴England | 33 | 0 | 0 | 1.8 | 23▲513.5%↩ | 16▼33.3%↩ |
| A. JulioAttacking midfielder | FC Dallas | 🇪🇨Ecuador | 30 | 6 | 1 | 3.5 | 23▼27.2%↩ | 24▼24.9%↩ |
| Z. GozoWinger |  Real Salt Lake | 🇺🇸USA | 19 | 4 | 3 | 6.9 | 23 | 46▲27.2% |
| P. JuddCentre-forward |  San Jose Earthquakes | 🇺🇸USA | 27 | 6 | 2 | 7 | 22▲355.1% | 33▼7.8% |
| D. EdelmanCentral midfielder | New York Red Bulls | 🇺🇸USA | 23 | 1 | 0 | 7.9 | 22▲13.8% | 42▼8.6% |
| E. ThommyWinger |  Sporting Kansas City | 🇩🇪Germany | 31 | 4 | 4 | 2.6 | 22▼35.5% | 19▼39.9% |
| RodriguesFull-back | San Jose Earthquakes | 🇧🇷Brazil | 28 | 1 | 1 | 4.2 | 22▲6.2% | 28▼29.2% |
| T. D'AvillaDefensive midfielder |  Chicago Fire | 🇨🇮Côte d'Ivoire | 23 | 2 | 1 | 7.7 | 22▲391.1%↩ | 41▼17.6%↩ |
| L. LangoniCentral midfielder |  New England Revolution | 🇦🇷Argentina | 24 | 2 | 2 | 8.1 | 22▲128.1%↩ | 43▼13.5%↩ |
| R. VeselinovićCentre-back | Vancouver Whitecaps | 🇷🇸Serbia | 27 | 0 | 0 | 6.7 | 22▼7.7% | 34▼22.6% |
| J. BartlettDefensive midfielder | Sporting Kansas City | 🇺🇸USA | 20 | 0 | 1 | 6.6 | 21 | 41 |
| A. GodoyCentral midfielder |  San Diego | 🇵🇦Panama | 36 | 1 | 1 | 1.3 | 21▼19.8%↩ | 14▲17.4%↩ |
| B. KamungoCentral midfielder | FC Dallas | 🇹🇿Tanzania | 24 | 2 | 1 | 7.5 | 21▲183.8% | 40▼1.7% |
| A. RickGoalkeeper | Philadelphia Union | 🇺🇸USA | 20 | 0 | 0 | 6.6 | 21▲1212.5% | 42▲9.2% |
| R. PrisoCentral midfielder | Vancouver Whitecaps | 🇨🇦Canada | 24 | 1 | 2 | 7.8 | 21▲328.6% | 42▲8% |
| A. OjedaCentral midfielder |  New York City FC | 🇦🇷Argentina | 22 | 0 | 5 | 7.5 | 21▲105.9% | 42▲0.7% |
| J. MorrisCentre-forward | Seattle Sounders | 🇺🇸USA | 31 | 7 | 1 | 2.6 | 21▼57.1% | 19▼43% |
| Y. CheberkoCentre-back |  Columbus Crew | 🇺🇦Ukraine | 28 | 0 | 0 | 3.9 | 21▼24.8% | 31▼18% |
| Y. BrightDefensive midfielder |  Inter Miami | 🇮🇹Italy | 24 | 1 | 1 | 7.2 | 21▼3.7% | 38▼13.6% |
| J. GallagherCentre-back |  Austin | 🇮🇪Republic of Ireland | 30 | 2 | 0 | 3.2 | 21▼8.8% | 26▼22.5% |
| B. VeraCentre-back | Real Salt Lake | 🇨🇴Colombia | 27 | 1 | 0 | 6.4 | 21▼23.4% | 34▼16.6% |
| N. AllenCentre-back | Inter Miami | 🇺🇸USA | 22 | 0 | 1 | 7.7 | 20▲106.1% | 43▲3.3% |
| L. BartlettCentre-back |  DC United | 🇺🇸USA | 29 | 0 | 0 | 3.5 | 20▲32.7% | 30▼18% |
| C. GarcésCentre-back |  Los Angeles Galaxy | 🇨🇴Colombia | 24 | 1 | 1 | 7.1 | 20▲64.2% | 38▼4% |
| K. ThompsonDefensive midfielder |  Toronto FC | 🇨🇦Canada | 23 | 0 | 0 | 8 | 20▲137.6% | 43▲10% |
| P. de la VegaWinger | Seattle Sounders | 🇦🇷Argentina | 25 | 4 | 4 | 7.5 | 20▲189.9% | 40▲8% |
| W. ZimmermanFull-back | Nashville SC | 🇺🇸USA | 33 | 0 | 2 | 1.5 | 20▼18.4% | 14▼30.5% |
| C. HarrisCentre-forward | Colorado Rapids | 🏴England | 26 | 5 | 1 | 6.6 | 20▲20.6% | 35▼13.9% |
| M. FalcónCentre-back | Inter Miami | 🇺🇾Uruguay | 29 | 1 | 0 | 3.4 | 20 | 28 |
| D. MartínezWinger |  Los Angeles FC | 🇻🇪Venezuela | 20 | 3 | 5 | 7.2 | 20▲57.1% | 45▲6.8% |
| M. MiazgaCentre-back | FC Cincinnati | 🇺🇸USA | 31 | 0 | 1 | 2.8 | 20▲31.3% | 21▼20.2% |
| J. FernándezWinger | New York City FC | 🇦🇷Argentina | 22 | 3 | 5 | 7.5 | 20▲94.1% | 42▲0.7% |
| J. OsorioCentre-forward | Toronto FC | 🇨🇦Canada | 34 | 4 | 1 | 1.3 | 19▼7.2% | 14▼23.2% |
| M. YamaneFull-back | Los Angeles Galaxy | 🇯🇵Japan | 32 | 1 | 4 | 2.4 | 19▼36.8% | 19▼31.9% |
| Igor JesusDefensive midfielder | Los Angeles FC | 🇧🇷Brazil | 23 | 0 | 1 | 8 | 19▲124.4%↩ | 43▼20.9%↩ |
| Jordi AlbaFull-back | Inter Miami | 🇪🇸Spain | 37 | 6 | 14 | 1.1 | 19▲26.3% | 14▼18% |
| T. OstrákCentral midfielder |  St. Louis City | 🇨🇿Czechia | 26 | 1 | 2 | 6.3 | 19▲97.9% | 33▼11.2% |
| O. BrynhildsenWinger | Toronto FC | 🇳🇴Norway | 27 | 2 | 1 | 6.7 | 19▼42.2%↩ | 36▼13.8%↩ |
| M. SofoWinger | New York Red Bulls | 🇬🇭Ghana | 21 | 5 | 0 | 7.4 | 19 | 44▲20.7% |
| D. CharáDefensive midfielder |  Portland Timbers | 🇨🇴Colombia | 40 | 0 | 1 | 0.6 | 19▼5% | 7▼36% |
| D. RíosCentre-forward | Vancouver Whitecaps | 🇲🇽Mexico | 31 | 4 | 3 | 2.7 | 19▼12.4%↩ | 21▼19.1%↩ |
| M. AmundsenFull-back | Columbus Crew | 🇩🇰Denmark | 28 | 1 | 2 | 3.6 | 19▼50.4% | 30▼24.4% |
| P. DelgadoAttacking midfielder | FC Dallas | 🇪🇨Ecuador | 22 | 1 | 6 | 7.7 | 19▼18.5% | 43▲0.9% |
| S. FreiGoalkeeper | Seattle Sounders | 🇺🇸USA | 40 | 0 | 0 | 0.9 | 19▼48.6% | 12▼3.3% |
| M. DeslerFull-back | Austin | 🇩🇰Denmark | 31 | 1 | 3 | 2.7 | 19▲220.3% | 20▼5.6% |
| S. IbeaghaCentre-back | FC Dallas | 🇺🇸USA | 34 | 1 | 0 | 1.6 | 19▼12.1% | 17▼24.1% |
| A. IvačičGoalkeeper | New England Revolution | 🇸🇮Slovenia | 32 | 0 | 0 | 2.3 | 19▲198.4% | 20▼19% |
| E. EneliCentral midfielder | Real Salt Lake | 🇺🇸USA | 26 | 0 | 1 | 6.8 | 19▼47.9% | 36▼18.4% |
| N. Fernández MercauAttacking midfielder | New York City FC | 🇦🇷Argentina | 26 | 5 | 2 | 6.9 | 19▼48.8%↩ | 37▼47.5%↩ |
| J. ShoreDefensive midfielder | New York City FC | 🇺🇸USA | 19 | 1 | 0 | 6.3 | 19 | 42 |
| K. Kossa-RienziFull-back | Seattle Sounders | 🇺🇸USA | 24 | 3 | 2 | 8 | 19▲9300% | 43▲24.3% |
| R. PetrettaCentre-back | Toronto FC | 🇮🇹Italy | 29 | 0 | 0 | 3.2 | 19▼16.1% | 27▼20.4% |
| J. MaherCentre-back | Nashville SC | 🇺🇸USA | 26 | 0 | 0 | 7.4 | 19▼29.7% | 40▼5.5% |
| D. ŽuparićCentre-back | Portland Timbers | 🇭🇷Croatia | 34 | 0 | 0 | 1.1 | 19▼20.2% | 12▼39% |
| J. DeanFull-back | Chicago Fire | 🇺🇸USA | 29 | 1 | 4 | 3.2 | 19▲43.4% | 28▼2.8% |
| T. ChancalayCentre-forward | New England Revolution | 🇦🇷Argentina | 27 | 4 | 2 | 6.1 | 19▲74.5% | 33▼8.6% |
| T. Ku-DiPietroCentral midfielder | Colorado Rapids | 🇺🇸USA | 24 | 1 | 3 | 7.2 | 19▼34.9%↩ | 39▼10.2%↩ |
| T. SpicerWinger | Toronto FC | 🇹🇹Trinidad and Tobago | 25 | 4 | 2 | 7.4 | 19▲68.2% | 40▲3.1% |
| J. GresselCentral midfielder |  Minnesota United FC | 🇺🇸USA | 32 | 1 | 3 | 1.9 | 18▼40.4%↩ | 16▼42.4%↩ |
| M. Haile-SelassieAttacking midfielder | Chicago Fire | 🇨🇭Switzerland | 27 | 2 | 6 | 6.1 | 18▼38.8% | 33▼18.7% |
| M. FarsiCentral midfielder | Columbus Crew | 🇨🇦Canada | 26 | 1 | 3 | 6.8 | 18▼19.4% | 36▼19.4% |
| J. RosalesFull-back | Minnesota United FC | 🇭🇳Honduras | 25 | 1 | 2 | 7.7 | 18▼59.1% | 41▼9.6% |
| Ilie SánchezCentral midfielder | Austin | 🇪🇸Spain | 35 | 1 | 0 | 1.2 | 18▼32.1%↩ | 13▼18.3%↩ |
| B. ŠabovićCentral midfielder | Austin | 🇸🇪Sweden | 28 | 1 | 0 | 3.4 | 18▼24.8%↩ | 30▼6.5%↩ |
| B. VázquezCentre-forward | Austin | 🇺🇸USA | 27 | 5 | 0 | 6.4 | 18▼46%↩ | 34▼28.2%↩ |
| Jansen MillerCentre-back | Sporting Kansas City | 🇺🇸USA | 24 | 0 | 1 | 7.6 | 18 | 40 |
| R. De PaulCentral midfielder | Inter Miami | 🇦🇷Argentina | 32 | 1 | 4 | 2 | 18▼52.5%↩ | 16▼68.2%↩ |
| M. KayeDefensive midfielder | San Jose Earthquakes | 🇨🇦Canada | 31 | 1 | 1 | 2.4 | 18▲31.2%↩ | 17▼28.6%↩ |
| P. OrtízCentre-back | Houston Dynamo | 🇨🇴Colombia | 26 | 1 | 0 | 6.4 | 18▲302.2%↩ | 34▼8.6%↩ |
| M. LongstaffCentral midfielder | Toronto FC | 🏴England | 26 | 0 | 2 | 6.9 | 18▼38.2% | 37▼11.1% |
| R. LaryeaCentral midfielder | Toronto FC | 🇨🇦Canada | 31 | 1 | 1 | 2.5 | 18▲130.8% | 18▼23.4% |
| M. DominguezDefensive midfielder | Toronto FC | 🇨🇭Switzerland | 30 | 0 | 1 | 2.8 | 18▲373.7%↩ | 22▼43.8%↩ |
| J. WatermanCentre-back |  CF Montreal | 🇨🇦Canada | 30 | 1 | 1 | 2.8 | 18▼40% | 25▼20.6% |
| B. AnungaDefensive midfielder | FC Cincinnati | 🇨🇲Cameroon | 29 | 0 | 1 | 3.1 | 18▲32.4%↩ | 26▼16.5%↩ |
| A. WattsDefensive midfielder | St. Louis City | 🇺🇸USA | 26 | 1 | 0 | 6.4 | 18▲42.9% | 34▼8.4% |
| M. SuleymanovWinger | Sporting Kansas City | 🇷🇺Russia | 26 | 2 | 3 | 6.8 | 18▲300%↩ | 36▲6.2%↩ |
| B. StuverGoalkeeper | Austin | 🇺🇸USA | 35 | 0 | 0 | 1.7 | 18▲10.6% | 18▼8% |
| W. CarmonaCentral midfielder | New York Red Bulls | 🇻🇪Venezuela | 23 | 0 | 1 | 7.8 | 18▼32.6% | 42▼7.3% |
| BrennerCentre-forward | FC Cincinnati | 🇧🇷Brazil | 26 | 6 | 1 | 6.6 | 18▲91.3%↩ | 35▼47.9%↩ |
| Obafemi AwodesuCentre-back | Houston Dynamo | 🇺🇸USA | 25 | 1 | 0 | 7.1 | 18 | 38 |
| J. ShaffelburgCentre-forward | Nashville SC | 🇨🇦Canada | 26 | 4 | 2 | 6.8 | 18▲8.7% | 36▼8.3% |
| C. ParedesDefensive midfielder | Portland Timbers | 🇵🇾Paraguay | 28 | 2 | 0 | 3.3 | 17▼5.4% | 28▼23.2% |
| C. RamirezCentre-forward | Los Angeles Galaxy | 🇺🇸USA | 35 | 4 | 2 | 0.9 | 17▼44.2%↩ | 10▼36%↩ |
| N. HagglundCentre-back | FC Cincinnati | 🇺🇸USA | 33 | 1 | 0 | 1.6 | 17▲394.3% | 15▼3.2% |
| A. BassiCentre-forward | Houston Dynamo | 🇲🇦Morocco | 28 | 2 | 3 | 3.3 | 17▼45.6% | 29▼28.9% |
| J. NelsonWinger | Vancouver Whitecaps | 🇨🇦Canada | 23 | 2 | 5 | 8 | 17▲152.9%↩ | 43▲5.4%↩ |
| T. BaumgartlCentre-back | St. Louis City | 🇩🇪Germany | 30 | 0 | 1 | 2.7 | 17▲83.9%↩ | 22▼47.9%↩ |
| J. WillisGoalkeeper | Nashville SC | 🇺🇸USA | 37 | 0 | 0 | 1.1 | 17▼17.6% | 14▼8.3% |
