| M. PolsterDefensive midfielder |  New England Revolution | 🇺🇸USA | 33 | 1 | 1 | 1.9 | 30▲22.8% | 17▼24.3% |
| L. CampanaCentre-forward | New England Revolution | 🇪🇨Ecuador | 26 | 7 | 1 | 9.3 | 30▲15.1%↩ | 39▼11.7%↩ |
| B. VázquezCentre-forward |  Austin | 🇺🇸USA | 27 | 5 | 0 | 9.3 | 30▼11.9%↩ | 38▼19.6%↩ |
| D. YapiAttacking midfielder |  Colorado Rapids | 🇺🇸USA | 21 | 8 | 2 | 8.4 | 30▲217% | 45▲7.2% |
| I. AnguloCentral midfielder |  Orlando City SC | 🇨🇴Colombia | 27 | 0 | 4 | 9.3 | 30▼34.2% | 37▼24% |
| T. JohnsonFull-back |  Vancouver Whitecaps | 🇺🇸USA | 21 | 1 | 1 | 8.4 | 30 | 46 |
| Q. SullivanAttacking midfielder |  Philadelphia Union | 🇺🇸USA | 22 | 2 | 7 | 8.9 | 30▼18.3% | 46▼3.8% |
| A. LongCentre-back |  Los Angeles FC | 🇺🇸USA | 33 | 1 | 0 | 1.9 | 30▼24.8% | 17▼26.2% |
| V. LoturiDefensive midfielder |  CF Montreal | 🇨🇦Canada | 25 | 2 | 0 | 9.4 | 30▲1410%↩ | 42▲12.6%↩ |
| C. CappisCentral midfielder |  FC Dallas | 🇺🇸USA | 26 | 1 | 2 | 9.4 | 30▲350.7%↩ | 38▲3.2%↩ |
| E. Latte LathCentre-forward |  Atlanta United FC | 🇨🇮Côte d'Ivoire | 27 | 7 | 1 | 9.5 | 30▼9.6%↩ | 37▼43.8%↩ |
| N. TafariCentre-back | Los Angeles FC | 🇺🇸USA | 29 | 0 | 0 | 4.8 | 31▲59.1%↩ | 28▼23.1%↩ |
| M. UzuniCentre-forward | Austin | 🇦🇱Albania | 31 | 6 | 3 | 3.4 | 31▼16.1%↩ | 24▼40.4%↩ |
| A. JulioCentral midfielder | FC Dallas | 🇪🇨Ecuador | 30 | 6 | 1 | 3.7 | 31▼0.6%↩ | 24▼23.3%↩ |
| K. YeboahCentre-forward |  Minnesota United FC | 🇮🇹Italy | 26 | 9 | 0 | 9.7 | 31▲22.4% | 41▼1.2% |
| A. CubasDefensive midfielder | Vancouver Whitecaps | 🇵🇾Paraguay | 30 | 0 | 1 | 4.3 | 31▲13.5% | 27▼12.5% |
| T. BeasonFull-back | New England Revolution | 🇺🇸USA | 29 | 0 | 1 | 4.7 | 32▲246.2%↩ | 28▼14.3%↩ |
| M. BoxallCentre-back | Minnesota United FC | 🇳🇿New Zealand | 37 | 1 | 1 | 1 | 32▲38.8% | 13▼21.2% |
| M. MoralezAttacking midfielder |  New York City FC | 🇦🇷Argentina | 39 | 3 | 9 | 1 | 32▲117.2% | 13▲109.4% |
| O. LarrazDefensive midfielder | Colorado Rapids | 🇺🇸USA | 24 | 0 | 3 | 9.9 | 32▲5% | 43▼0.7% |
| I. HarkesCentral midfielder |  San Jose Earthquakes | 🇺🇸USA | 31 | 3 | 2 | 3.1 | 32▲109.3%↩ | 22▼9.3%↩ |
| A. BlakeGoalkeeper | Philadelphia Union | 🇯🇲Jamaica | 35 | 0 | 0 | 1.3 | 32▲358% | 14▲22.4% |
| A. MiranchukCentre-forward | Atlanta United FC | 🇷🇺Russia | 30 | 6 | 3 | 4.5 | 32▲88.7% | 29±0% |
| L. de la TorreCentral midfielder |  San Diego | 🇺🇸USA | 28 | 5 | 1 | 6 | 32 | 35▼38.1%↩ |
| M. RobinsonCentre-back |  FC Cincinnati | 🇺🇸USA | 29 | 2 | 0 | 5.5 | 32▲7.4% | 32▼13.3% |
| R. CannonFull-back | Colorado Rapids | 🇺🇸USA | 28 | 0 | 0 | 6 | 32▲720.5% | 33▲2.8% |
| L. EnnaliCentral midfielder |  Houston Dynamo | 🇩🇪Germany | 24 | 1 | 4 | 10 | 32▲1433.3% | 41▲5.4% |
| T. SegoviaAttacking midfielder |  Inter Miami | 🇻🇪Venezuela | 23 | 9 | 4 | 10.1 | 32▲76.1%↩ | 45▼24.7%↩ |
| J. BambaWinger |  Chicago Fire | 🇨🇮Côte d'Ivoire | 30 | 6 | 5 | 4.4 | 32▲620%↩ | 28▼44.2%↩ |
| Gabriel PiraniWinger |  DC United | 🇧🇷Brazil | 24 | 7 | 3 | 10.2 | 33▲46.2% | 44▲5.5% |
| Guilherme BiroFull-back | Austin | 🇧🇷Brazil | 26 | 3 | 1 | 10.3 | 33▲33.1% | 41▼6.5% |
| C. dos SantosGoalkeeper | San Diego | 🇺🇸USA | 25 | 0 | 0 | 10.3 | 33 | 46▲27.9%↩ |
| G. DorseyFull-back | Houston Dynamo | 🇺🇸USA | 27 | 2 | 4 | 10.3 | 33▼6% | 38▼12.3% |
| D. SallóiAttacking midfielder |  Sporting Kansas City | 🇭🇺Hungary | 30 | 7 | 3 | 4 | 33▲56.1% | 26▼20.8% |
| D. LovitzFull-back |  Nashville SC | 🇺🇸USA | 34 | 2 | 5 | 1.6 | 33▲29.7% | 17▼11.5% |
| Y. GómezCentre-back |  Seattle Sounders | 🇨🇴Colombia | 34 | 0 | 1 | 1.4 | 33▼25.7% | 15▼27.8% |
| C. BassettDefensive midfielder | Colorado Rapids | 🇺🇸USA | 25 | 3 | 3 | 10.4 | 33▼12.3% | 45▼5.5% |
| T. GrayFull-back | New York City FC | 🇯🇲Jamaica | 23 | 0 | 0 | 10.4 | 33▲98.8% | 44▼2% |
| E. SabbiAttacking midfielder | Vancouver Whitecaps | 🇺🇸USA | 28 | 8 | 3 | 6.3 | 34 | 35▼34.6%↩ |
| D. PereiraCentral midfielder | Austin | 🇻🇪Venezuela | 26 | 2 | 3 | 10.5 | 34▲16.3% | 41▼4.9% |
| A. WestwoodDefensive midfielder |  Charlotte | 🏴England | 36 | 1 | 4 | 1.7 | 34▲1.2% | 18▼1.6% |
| C. HarveyCentre-back | Minnesota United FC | 🇵🇦Panama | 26 | 2 | 1 | 10.6 | 34▲148.2% | 40▲3.7% |
| A. NajarFull-back | Nashville SC | 🇭🇳Honduras | 33 | 2 | 7 | 2.1 | 34▲85.8%↩ | 19▼4.5%↩ |
| R. HollingsheadFull-back | Los Angeles FC | 🇺🇸USA | 35 | 2 | 4 | 1.5 | 34▼17% | 16▼7.2% |
| Son Heung-MinCentre-forward | Los Angeles FC | 🇰🇷Korea Republic | 34 | 12 | 3 | 1.1 | 34▼27.6%↩ | 11▼69.5%↩ |
| Thiago MartinsCentre-back | New York City FC | 🇧🇷Brazil | 31 | 1 | 0 | 3.6 | 35▲90.1% | 26▼17.6% |
| I. FeingoldCentral midfielder | New England Revolution | 🇮🇱Israel | 21 | 3 | 3 | 9.8 | 35 | 48 |
| PeglowCentral midfielder | DC United | 🇧🇷Brazil | 24 | 3 | 3 | 10.9 | 35▲330.9%↩ | 44▲27%↩ |
| D. GazdagAttacking midfielder |  Columbus Crew | 🇭🇺Hungary | 30 | 6 | 5 | 4.5 | 35▼36.1%↩ | 29▼14.5%↩ |
| Y. TakaokaGoalkeeper | Vancouver Whitecaps | 🇯🇵Japan | 30 | 0 | 1 | 4.7 | 35▲104.7% | 30▼14.5% |
| F. EscobarFull-back | Houston Dynamo | 🇦🇷Argentina | 31 | 2 | 2 | 3.1 | 35▲7.3% | 22▼19.5% |
| Gabriel PecWinger |  Los Angeles Galaxy | 🇧🇷Brazil | 25 | 7 | 3 | 11 | 35▼49.2% | 44▼13.9% |
| Felipe AndradeFull-back | Houston Dynamo | 🇧🇷Brazil | 24 | 4 | 1 | 11.1 | 36▲624.5%↩ | 43▼25%↩ |
| D. SealyAttacking midfielder | CF Montreal | 🇺🇸USA | 23 | 9 | 1 | 11.1 | 36▲600%↩ | 46▲18.8%↩ |
| T. BlackmonCentre-back | Vancouver Whitecaps | 🇺🇸USA | 29 | 2 | 1 | 5.3 | 36▲115% | 31▼9.6% |
| P. BuchaDefensive midfielder | FC Cincinnati | 🇨🇿Czechia | 28 | 4 | 5 | 6.6 | 36▼10.9% | 35▼20.5% |
| E. AtuestaCentral midfielder | Orlando City SC | 🇨🇴Colombia | 29 | 0 | 6 | 5.3 | 36▲1.1%↩ | 31▼14%↩ |
| A. MarkanichFull-back | Minnesota United FC | 🇺🇸USA | 26 | 10 | 1 | 11.3 | 36▲438.8%↩ | 40▲2.6%↩ |
| M. HerreraDefensive midfielder | Columbus Crew | 🇦🇷Argentina | 27 | 5 | 3 | 11.1 | 36▲29.7%↩ | 36▼25.4%↩ |
| K. O'TooleFull-back | New York City FC | 🇺🇸USA | 27 | 1 | 1 | 11.4 | 37▲202.5% | 37▼14.1% |
| A. YusufCentral midfielder | New England Revolution | 🇳🇬Nigeria | 26 | 2 | 1 | 11.5 | 37▲353.1% | 41▲17.7% |
| R. VeselinovićCentre-back | Vancouver Whitecaps | 🇷🇸Serbia | 27 | 0 | 0 | 11.5 | 37▲56.8% | 38▼12.3% |
| W. TrappCentral midfielder | Minnesota United FC | 🇺🇸USA | 33 | 2 | 2 | 2.1 | 37▲32% | 19▼16.8% |
| J. MorrisCentre-forward | Seattle Sounders | 🇺🇸USA | 31 | 7 | 1 | 3.1 | 37▼24.4% | 22▼33.3% |
| M. DeslerCentral midfielder | Austin | 🇩🇰Denmark | 31 | 1 | 3 | 3.2 | 37▲527.1% | 23▲7.5% |
| M. ReusAttacking midfielder | Los Angeles Galaxy | 🇩🇪Germany | 37 | 5 | 8 | 0.7 | 37▲332.6% | 9▲15% |
| A. PereaDefensive midfielder | New York City FC | 🇺🇸USA | 25 | 3 | 2 | 11.7 | 38▲72.5% | 43▲4.4% |
| D. ChambostDefensive midfielder | Columbus Crew | 🇫🇷France | 28 | 2 | 5 | 6.5 | 38▲310.9% | 35±0% |
| E. SeguraCentre-back | Los Angeles FC | 🇨🇴Colombia | 29 | 1 | 2 | 5.3 | 38▲110.6% | 31▼0.6% |
| D. FagundezCentral midfielder | Los Angeles Galaxy | 🇺🇾Uruguay | 31 | 6 | 2 | 3.3 | 38▲72.4% | 23▼12.7% |
| K. KahlinaGoalkeeper | Charlotte | 🇭🇷Croatia | 34 | 0 | 0 | 1.6 | 38▲11% | 17▼27% |
| M. HartelAttacking midfielder |  St. Louis City | 🇩🇪Germany | 30 | 9 | 4 | 4.6 | 39▲104.8% | 30▲3.5% |
| I. VassilevCentral midfielder | Philadelphia Union | 🇺🇸USA | 25 | 6 | 3 | 12 | 39▲45.1%↩ | 44▼1.1%↩ |
| L. MurielCentre-forward | Orlando City SC | 🇨🇴Colombia | 35 | 9 | 5 | 1.4 | 39▲57.6% | 15▲2.7% |
| João KlaussCentre-forward | St. Louis City | 🇧🇷Brazil | 29 | 10 | 2 | 5 | 39▲72.8% | 29▼17.2% |
| D. Jean-JacquesCentral midfielder | Philadelphia Union | 🇭🇹Haiti | 26 | 3 | 2 | 12.2 | 39▲766.7% | 40▲15.7% |
| É. OcampoFull-back | Vancouver Whitecaps | 🇨🇴Colombia | 22 | 2 | 0 | 11.6 | 39▲3810% | 47▲30.4% |
| D. AyalaDefensive midfielder |  Portland Timbers | 🇦🇷Argentina | 24 | 2 | 1 | 12.2 | 39▲61.3% | 44▲7.4% |
| E. PonceCentre-forward | Houston Dynamo | 🇦🇷Argentina | 29 | 10 | 1 | 5.3 | 39▲154.5% | 31▼1.6% |
| C. McVeyCentre-back | San Diego | 🇸🇪Sweden | 29 | 2 | 0 | 5.6 | 39▲7.4%↩ | 33▼2.7%↩ |
| I. Toklomati GiornoCentre-forward | Charlotte | 🇮🇱Israel | 21 | 12 | 3 | 11.1 | 39 | 48▲29.9% |
| B. CeballosCentre-back | New England Revolution | 🇨🇴Colombia | 25 | 1 | 0 | 12.4 | 40▲1000%↩ | 43▲19.3%↩ |
| M. IloskiCentre-forward | Philadelphia Union | 🇺🇸USA | 27 | 13 | 6 | 11 | 40▲510.8%↩ | 35±0% |
| C. BentekeCentre-forward | DC United | 🇧🇪Belgium | 35 | 9 | 3 | 1.4 | 40▼44% | 15▼22.4% |
| T. ReamCentre-back | Charlotte | 🇺🇸USA | 38 | 0 | 0 | 1 | 41▲202.2% | 13▲28.9% |
| O. WolffWinger | Austin | 🇺🇸USA | 21 | 7 | 8 | 11.5 | 41▲100.5% | 50▲15.6% |
| C. RoldanDefensive midfielder | Seattle Sounders | 🇺🇸USA | 31 | 1 | 3 | 3.5 | 41▲26.2% | 25▼19.7% |
| D. LunaAttacking midfielder |  Real Salt Lake | 🇺🇸USA | 22 | 9 | 3 | 12.2 | 41▲13.2% | 49±0% |
| A. PellegrinoWinger | San Diego | 🇳🇴Norway | 36 | 7 | 4 | 1.4 | 42▲46.6%↩ | 15▲13.2%↩ |
| J. LukićCentral midfielder | Philadelphia Union | 🇷🇸Serbia | 24 | 2 | 2 | 13 | 42 | 45▲3.7%↩ |
| AntonyAttacking midfielder | Portland Timbers | 🇧🇷Brazil | 24 | 7 | 7 | 13 | 42▲42.2% | 48▲5.1% |
| J. HaakCentre-back | New York City FC | 🇺🇸USA | 24 | 2 | 4 | 13.1 | 42▲323.2% | 46▲17.6% |
| N. ByrneFull-back | Charlotte | 🏴England | 34 | 0 | 0 | 1.5 | 43▲15.2% | 16▼27.1% |
| W. ZahaAttacking midfielder | Charlotte | 🇨🇮Côte d'Ivoire | 33 | 10 | 5 | 2.2 | 43 | 21▼14.5%↩ |
| J. OsorioDefensive midfielder |  Toronto FC | 🇨🇦Canada | 34 | 4 | 1 | 1.6 | 43▲106.2% | 17▼6.2% |
| H. WolfAttacking midfielder | New York City FC | 🇦🇹Austria | 27 | 11 | 6 | 12.3 | 44▲38.5% | 39▼13.2% |
| Sergio BusquetsCentral midfielder | Inter Miami | 🇪🇸Spain | 38 | 0 | 8 | 1.1 | 44▲19.3% | 14▼14.6% |
| M. LabordaCentre-back | Vancouver Whitecaps | 🇺🇾Uruguay | 26 | 6 | 1 | 13.7 | 44▲86.9% | 44▲6% |
| Beau LerouxCentral midfielder | San Jose Earthquakes | 🇺🇸USA | 22 | 5 | 3 | 13.1 | 44 | 47 |
| Sergi PalenciaFull-back | Los Angeles FC | 🇪🇸Spain | 30 | 1 | 2 | 4.5 | 45▲6.3% | 29▼11.3% |
