| M. WhittakerCentre-forward |  Colorado Rapids | 🏴England | 25 | 1 | 0 | 0 | 6.1 | 48±0% | 72±0% |
| Cherrion ValeriusFull-back |  Minnesota United FC | 🇨🇼Curaçao | 21 | 4 | 0 | 0 | 7.8 | 25±0% | 66±0% |
| Ramon RiquelmeCentral midfielder |  Inter Miami | 🇧🇷Brazil | 20 | 0 | 0 | 0 | 5.7 | 0 | 60 |
| J. MalatiniCentre-back | FC Cincinnati | 🇦🇷Argentina | 25 | 11 | 0 | 0 | 11.8 | 6▼7.2%↩ | 59▼16.1%↩ |
| D. DownsWinger |  St. Louis City | 🇩🇪Germany | 22 | 3 | 0 | 0 | 6.3 | 3 | 59▼7.9%↩ |
| L. WaltaDefensive midfielder |  Los Angeles FC | 🇫🇮Finland | 23 | 1 | 0 | 0 | 10.4 | 3▼93.9%↩ | 58▲43.1%↩ |
| J. GómezCentre-forward |  Chicago Fire | 🇺🇸USA | 25 | 2 | 0 | 0 | 6 | 20±0% | 58±0% |
| Rui ModestoCentral midfielder |  Vancouver Whitecaps | 🇦🇴Angola | 26 | 1 | 0 | 0 | 5.8 | 2▼60%↩ | 58▲13.6%↩ |
| T. SmithCentre-back | New England Revolution | 🇿🇦South Africa | 21 | 3 | 0 | 0 | 9.3 | 1 | 55 |
| Y. DiabyWinger | Vancouver Whitecaps | 🇬🇳Guinea | 26 | 3 | 0 | 0 | 5.8 | 38±0% | 55±0% |
| T. BoothCentre-forward |  Real Salt Lake | 🇺🇸USA | 25 | 1 | 0 | 0 | 5.9 | 4±0% | 55±0% |
| Arthur SousaCentre-forward |  Houston Dynamo | 🇧🇷Brazil | 23 | 6 | 0 | 0 | 10 | 0 | 53▼9.7%↩ |
| I. SadiqCentre-forward | Colorado Rapids | 🇬🇭Ghana | 26 | 20 | 2 | 0 | 10.5 | 9▼69.9%↩ | 53▼20.3%↩ |
| S. RodríguezWinger |  Columbus Crew | 🇺🇾Uruguay | 26 | 3 | 2 | 0 | 6.5 | 20±0% | 52▼13.4%↩ |
| M. GalarzaCentral midfielder | Inter Miami | 🇵🇾Paraguay | 24 | 23 | 0 | 0 | 6.2 | 17▲43.7%↩ | 50▲6.6%↩ |
| M. Dos SantosCentre-back |  New York Red Bulls | 🏳️ | 17 | 21 | 0 | 0 | 6.5 | 15 | 50 |
| T. JohnsonCentre-back | Vancouver Whitecaps | 🇺🇸USA | 21 | 22 | 0 | 0 | 13.5 | 47▲60.1% | 49▲7.7% |
| M. Dos SantosCentre-back | New York Red Bulls | 🇺🇸USA | 18 | 23 | 0 | 0 | 6.7 | 14 | 48 |
| C. BradyGoalkeeper | Chicago Fire | 🇺🇸USA | 22 | 24 | 0 | 0 | 8.5 | 21▲177.6% | 48▲6.2% |
| R. RobertsCentre-back |  San Jose Earthquakes | 🇺🇸USA | 22 | 22 | 2 | 0 | 11.1 | 35▲311.9% | 47▲24.5% |
| Igor JesusCentral midfielder | Los Angeles FC | 🇧🇷Brazil | 23 | 2 | 0 | 0 | 6.6 | 30▲53.9% | 47▲9.1% |
| B. RainesCentral midfielder |  New England Revolution | 🇺🇸USA | 21 | 23 | 1 | 0 | 8.5 | 32▲164.7%↩ | 47▲13.4%↩ |
| A. ReschCentre-back | Houston Dynamo | 🏳️ | 23 | 23 | 1 | 0 | 14.3 | 53 | 46 |
| E. KohlerCentre-back | New England Revolution | 🏳️ | 20 | 18 | 0 | 0 | 7.3 | 25 | 46▲24.1%↩ |
| N. NorrisCentre-back |  FC Dallas | 🇺🇸USA | 21 | 20 | 1 | 0 | 7.7 | 27▲341% | 46▲13.4% |
| M. AgyemangCentre-back |  Charlotte | 🇬🇭Ghana | 21 | 20 | 2 | 0 | 7.6 | 19 | 45 |
| Felipe AndradeCentre-back | Houston Dynamo | 🇧🇷Brazil | 24 | 19 | 1 | 0 | 14.9 | 50▲78.4% | 45▲9.2% |
| CalegariCentre-back |  Los Angeles Galaxy | 🇧🇷Brazil | 24 | 1 | 0 | 0 | 6.2 | 24▲31.9%↩ | 45▼1.1%↩ |
| M. WoledziCentre-back |  Nashville SC | 🇬🇭Ghana | 25 | 25 | 2 | 0 | 13.9 | 61▲24%↩ | 45▲2.8%↩ |
| O. VerhoevenCentre-back |  San Diego | 🇺🇸USA | 20 | 23 | 0 | 0 | 7.1 | 26▲130.7% | 45▲6.2% |
| P. SchulteGoalkeeper | Columbus Crew | 🇺🇸USA | 25 | 25 | 0 | 0 | 8.3 | 10▲21.5% | 45▲6% |
| J. RuvalcabaCentre-forward | New York Red Bulls | 🇲🇽Mexico | 25 | 24 | 7 | 0 | 10.9 | 36▲58%↩ | 44▼11.9%↩ |
| M. CorcoranCentral midfielder | Nashville SC | 🇺🇸USA | 20 | 22 | 0 | 0 | 7.2 | 15▲274.4% | 44▲17.2% |
| M. DugganCentre-back | Minnesota United FC | 🇩🇪Germany | 25 | 24 | 1 | 0 | 9.5 | 30▲85.8% | 44▲7.1% |
| H. OjediranDefensive midfielder | Colorado Rapids | 🇳🇬Nigeria | 22 | 22 | 1 | 0 | 8.6 | 26▲107.9%↩ | 44▼38.2%↩ |
| M. PeltolaDefensive midfielder |  DC United | 🇫🇮Finland | 24 | 25 | 1 | 0 | 10.2 | 33▲112.8% | 44▲10.6% |
| S. FarhiCentre-forward | Colorado Rapids | 🇮🇱Israel | 20 | 1 | 0 | 0 | 5.8 | 22±0% | 44±0% |
| R. ElloumiCentre-forward | Vancouver Whitecaps | 🇨🇦Canada | 19 | 19 | 2 | 0 | 6.5 | 10▲104% | 44▲5.8% |
| D. BugajFull-back |  CF Montreal | 🇵🇱Poland | 22 | 20 | 0 | 0 | 7.6 | 25▲77.9% | 43▲4.6% |
| Jayden HibbertGoalkeeper |  Atlanta United FC | 🇯🇲Jamaica | 22 | 8 | 0 | 0 | 7.6 | 4 | 43 |
| A. CvetkovićCentral midfielder | Vancouver Whitecaps | 🇷🇸Serbia | 21 | 1 | 0 | 0 | 6.3 | 33▲5.7%↩ | 43▲1.2%↩ |
| T. D'AvillaCentral midfielder | Chicago Fire | 🇨🇮Côte d'Ivoire | 23 | 23 | 1 | 0 | 8.5 | 27▲19.9% | 43▲5.4% |
| D. FerreeGoalkeeper | San Diego | 🇺🇸USA | 19 | 15 | 0 | 0 | 6.5 | 18 | 43 |
| J. WynderCentre-back | New England Revolution | 🇺🇸USA | 21 | 1 | 0 | 0 | 6 | 1±0% | 43±0% |
| K. Kossa-RienziDefensive midfielder |  Seattle Sounders | 🇺🇸USA | 24 | 21 | 3 | 0 | 11.3 | 37▲97.3% | 43±0% |
| K. ThompsonFull-back | Colorado Rapids | 🇨🇦Canada | 23 | 16 | 2 | 0 | 10.7 | 31▲51%↩ | 43±0% |
| M. MbokaziCentre-back | Chicago Fire | 🇿🇦South Africa | 21 | 12 | 0 | 0 | 10.5 | 22▼13.7%↩ | 43▲74.7%↩ |
| J. Marshall-RuttyCentre-back | New York Red Bulls | 🇨🇦Canada | 22 | 23 | 0 | 0 | 7.6 | 13▼50.2%↩ | 43±0% |
| D. VazquezCentral midfielder | San Diego | 🇺🇸USA | 20 | 18 | 3 | 0 | 8.4 | 25▲2350% | 43▲9.8% |
| Neil PierreCentre-back |  Philadelphia Union | 🇺🇸USA | 18 | 10 | 4 | 0 | 7.2 | 10▲2450% | 43▲17.3% |
| Luis OtávioDefensive midfielder |  Orlando City SC | 🇧🇷Brazil | 19 | 19 | 1 | 0 | 6.3 | 19▲125.3%↩ | 43▼29.7%↩ |
| P. DelgadoAttacking midfielder | FC Dallas | 🇪🇨Ecuador | 22 | 16 | 3 | 0 | 7.6 | 15▼18.9% | 43▼1.2% |
| R. CelentanoGoalkeeper |  FC Cincinnati | 🇺🇸USA | 26 | 23 | 0 | 0 | 7.5 | 3▼88.6% | 43▲3.9% |
| D. PolvaraCentre-back | St. Louis City | 🇺🇸USA | 26 | 25 | 1 | 0 | 9.2 | 31▲130.6%↩ | 42▲17.2%↩ |
| A. HezarkhaniWinger | Real Salt Lake | 🇺🇸USA | 19 | 20 | 2 | 0 | 6.4 | 12 | 42▲17% |
| J. CheCentre-back | New York Red Bulls | 🇺🇸USA | 22 | 17 | 0 | 0 | 9.9 | 19▼12.1%↩ | 42▼3.7%↩ |
| J. OrozcoCentre-back | St. Louis City | 🇺🇸USA | 22 | 18 | 0 | 0 | 8.5 | 19▲128.2% | 42▲13.6% |
| M. JimenezCentre-forward | New York Red Bulls | 🏳️ | 18 | 6 | 2 | 0 | 5.8 | 8 | 42 |
| L. GavranGoalkeeper |  Toronto FC | 🇨🇦Canada | 26 | 25 | 1 | 0 | 7.8 | 5▲73.3% | 42▲35.6% |
| A. GoodwinCentre-forward | Charlotte | 🇦🇺Australia | 21 | 22 | 3 | 0 | 6.9 | 13▲530% | 42▲12.4% |
| W. SandsCentre-back | New England Revolution | 🇺🇸USA | 26 | 25 | 1 | 0 | 8.1 | 28▲217% | 42▲27.3% |
| Emilio Aristizábal ChavarriagaCentre-forward | Toronto FC | 🇨🇴Colombia | 21 | 19 | 4 | 0 | 7.1 | 15▼51.3%↩ | 42▲39.7%↩ |
| IagoCentre-back | Orlando City SC | 🇧🇷Brazil | 21 | 16 | 0 | 0 | 7 | 10▲227.6%↩ | 41▼33.2%↩ |
| Leonardo BarrosoCentre-back | Chicago Fire | 🇵🇹Portugal | 21 | 13 | 0 | 0 | 7.2 | 18▲75.7% | 41▲4.3% |
| Z. MonlouisCentre-back | Toronto FC | 🏴England | 22 | 18 | 0 | 0 | 7.2 | 12▲287.5% | 41▲11.7% |
| Luighi HanriWinger |  New York City FC | 🇧🇷Brazil | 20 | 7 | 4 | 0 | 6.7 | 9▲129.3%↩ | 41▼36.4%↩ |
| J. AtencioCentral midfielder | Colorado Rapids | 🇺🇸USA | 24 | 21 | 1 | 0 | 7.9 | 20▼11.7% | 41▲3% |
| S. ZawadzkiCentral midfielder | Columbus Crew | 🇺🇸USA | 26 | 25 | 0 | 0 | 7.7 | 22▼29.6% | 41▲4.8% |
| Y. BrightDefensive midfielder | Inter Miami | 🇮🇹Italy | 25 | 21 | 0 | 0 | 10.2 | 27▲30.3% | 41▲10.2% |
| A. MartínezWinger | New York City FC | 🇨🇷Costa Rica | 27 | 1 | 0 | 0 | 4.8 | 59▲13.6% | 41▲5.9% |
| R. PrisoCentre-back | Vancouver Whitecaps | 🇨🇦Canada | 24 | 10 | 1 | 0 | 10.1 | 18▼16.2% | 41▼1.9% |
| Michael CollodiGoalkeeper | FC Dallas | 🇺🇸USA | 25 | 13 | 0 | 0 | 7.6 | 5▲25% | 41▲11.5% |
| M. GherasimencovFull-back | Vancouver Whitecaps | 🇺🇸USA | 21 | 8 | 0 | 0 | 6.8 | 13 | 41 |
| Alvaro AugustoCentre-back | FC Dallas | 🇧🇷Brazil | 21 | 4 | 0 | 0 | 6.8 | 13 | 41 |
| M. CimermancicCentral midfielder | Toronto FC | 🇨🇦Canada | 21 | 9 | 1 | 0 | 7 | 12▲342.3% | 40▲9.2% |
| A. ShawAttacking midfielder | Inter Miami | 🏳️ | 17 | 5 | 1 | 0 | 5.3 | 4 | 40 |
| C. DurkinDefensive midfielder | St. Louis City | 🇺🇸USA | 26 | 22 | 2 | 0 | 12.9 | 39▲186.1% | 40▲24.7% |
| E. TagsethDefensive midfielder | Nashville SC | 🇳🇴Norway | 25 | 20 | 1 | 0 | 9.2 | 24▼16% | 40▼5.2% |
| K. PokuCentre-forward | Vancouver Whitecaps | 🇨🇦Canada | 23 | 13 | 2 | 0 | 7.5 | 9▼26%↩ | 40▼9.6%↩ |
| I. GómezWinger | Orlando City SC | 🇦🇷Argentina | 20 | 2 | 1 | 0 | 6.4 | 2 | 40 |
| RaphaelFull-back | Vancouver Whitecaps | 🇧🇷Brazil | 22 | 6 | 2 | 0 | 7.1 | 6 | 40 |
| Gabriel PiraniCentral midfielder | San Diego | 🇧🇷Brazil | 24 | 8 | 0 | 0 | 7.6 | 21▼30.9%↩ | 40▼8%↩ |
| Jack JasinskiCentre-back | San Jose Earthquakes | 🇺🇸USA | 22 | 14 | 1 | 0 | 7.4 | 12 | 40 |
| J. GilmanCentre-back | Toronto FC | 🏳️ | 21 | 11 | 0 | 0 | 6.8 | 9 | 40 |
| J. NealCentre-back | CF Montreal | 🇺🇸USA | 23 | 14 | 0 | 0 | 7.5 | 12▲2.6% | 40▲6.6% |
| P. PlambeckAttacking midfielder | Inter Miami | 🏳️ | 19 | 6 | 1 | 0 | 6 | 4 | 40 |
| Chase AdamsCentre-forward | Columbus Crew | 🇺🇸USA | 18 | 6 | 1 | 0 | 5.6 | 4 | 40 |
| Daniel PinterCentre-forward | Inter Miami | 🇺🇸USA | 19 | 12 | 1 | 0 | 6 | 6 | 40 |
| K. TrewinCentre-back | New York City FC | 🇦🇺Australia | 25 | 15 | 0 | 0 | 9.5 | 17▲59.6%↩ | 40▲130.6%↩ |
| S. HawkinsCentre-back | Seattle Sounders | 🇺🇸USA | 20 | 9 | 1 | 0 | 6.8 | 14▲7100% | 40▲8.1% |
| G. YowWinger | New England Revolution | 🇺🇸USA | 23 | 20 | 1 | 0 | 7.2 | 8▼21.1%↩ | 40▼20.4%↩ |
| J. BazánCentre-back | New York Red Bulls | 🇨🇴Colombia | 20 | 11 | 0 | 0 | 6.4 | 12▲12000%↩ | 40▲83.9%↩ |
| C. CassanoWinger | Chicago Fire | 🇮🇹Italy | 23 | 9 | 1 | 0 | 7.5 | 6▲52.8%↩ | 40▼24.8%↩ |
| S. MohammedAttacking midfielder | Nashville SC | 🇬🇭Ghana | 23 | 15 | 3 | 0 | 7.8 | 14 | 40▲17.4%↩ |
| A. IbrahimCentre-forward | Houston Dynamo | 🇳🇬Nigeria | 24 | 18 | 2 | 0 | 7.4 | 10▼34.2%↩ | 40▼2.2%↩ |
| M. MaloneWinger | Minnesota United FC | 🇩🇪Germany | 26 | 3 | 0 | 0 | 5.4 | 17±0% | 40▼7.5%↩ |
| Loïc WilliamsCentre-back | Colorado Rapids | 🇪🇸Spain | 24 | 10 | 1 | 0 | 7.3 | 16▼54.5%↩ | 40▼37.7%↩ |
| M. GonzalezCentre-forward | Minnesota United FC | 🇨🇴Colombia | 22 | 14 | 2 | 0 | 6.8 | 8▼44.8%↩ | 40▲38.1%↩ |
| N. DefreitasGoalkeeper | Colorado Rapids | 🇩🇰Denmark | 25 | 14 | 0 | 0 | 7.5 | 18▲376.3% | 40▲11% |
| I. JamesCentre-back |  Sporting Kansas City | 🇺🇸USA | 18 | 13 | 0 | 0 | 6.4 | 9▲66.7% | 39▲7.4% |
