| Aymeric LaporteCentre-back |  Athletic Club | 🇪🇸Spain | 32 | 0 | 1 | 8.9 | 20▲6.6%↩ | 34▲9.1%↩ |
| J. OblakGoalkeeper |  Atletico Madrid | 🇸🇮Slovenia | 33 | 0 | 0 | 21.6 | 41▼39.1% | 34▼32.4% |
| P. CissDefensive midfielder |  Rayo Vallecano | 🇸🇳Senegal | 32 | 2 | 1 | 15.1 | 37▼13.6% | 34▼27.8% |
| Lucas TorróCentral midfielder |  Osasuna | 🇪🇸Spain | 32 | 0 | 1 | 10.8 | 25▼48% | 34▼33% |
| J. GiménezFull-back | Atletico Madrid | 🇺🇾Uruguay | 31 | 0 | 1 | 20.9 | 25▼44.2% | 35▼34.8% |
| GumbauCentral midfielder | Rayo Vallecano | 🇪🇸Spain | 31 | 0 | 3 | 10.3 | 21▲92.6% | 35▼22.2% |
| D. van de BeekCentral midfielder |  Girona | 🇳🇱Netherlands | 29 | 0 | 0 | 12.7 | 0▼98.8% | 35▼43.5% |
| Sergio HerreraGoalkeeper | Osasuna | 🇪🇸Spain | 33 | 0 | 0 | 8.1 | 14▼39.6% | 35▼26.6% |
| Dani CeballosDefensive midfielder |  Real Madrid | 🇪🇸Spain | 30 | 0 | 0 | 19.7 | 6▼53.8% | 36▼41.1% |
| A. ChristensenCentre-back |  Barcelona | 🇩🇰Denmark | 30 | 0 | 0 | 19.7 | 8▲62.5% | 36▼24.6% |
| J. AidooCentre-back |  Celta Vigo | 🇬🇭Ghana | 30 | 0 | 0 | 11.9 | 8▲256.5%↩ | 36▼19.2%↩ |
| C. LengletFull-back | Atletico Madrid | 🇫🇷France | 31 | 0 | 1 | 22.3 | 27▼56.5% | 36▼31.7% |
| C. StarfeltCentre-back | Celta Vigo | 🇸🇪Sweden | 31 | 0 | 0 | 10.8 | 19▼30.7% | 36▼32.3% |
| Javi GalánFull-back | Osasuna | 🇪🇸Spain | 31 | 0 | 1 | 12.3 | 25▼39.5%↩ | 36▼32.3%↩ |
| MarcãoCentre-back |  Sevilla | 🇧🇷Brazil | 30 | 0 | 0 | 12.1 | 8▼18.4% | 37▼19.4% |
| I. WilliamsAttacking midfielder | Athletic Club | 🇬🇭Ghana | 32 | 3 | 6 | 13.5 | 31▼32.5% | 37▼31.3% |
| David CostasCentre-back |  Oviedo | 🇪🇸Spain | 31 | 1 | 0 | 13.8 | 28▼4.5% | 37▼12.9% |
| DarderCentral midfielder |  Mallorca | 🇪🇸Spain | 32 | 1 | 5 | 16.7 | 39▼11.9% | 38▼26% |
| David SoriaGoalkeeper |  Getafe | 🇪🇸Spain | 33 | 0 | 0 | 13.7 | 35▲72.7% | 38▼20.5% |
| Nacho VidalFull-back | Oviedo | 🇪🇸Spain | 31 | 0 | 0 | 16.3 | 33▲50.9% | 39▼5.2% |
| Iván VillarGoalkeeper | Celta Vigo | 🇪🇸Spain | 29 | 0 | 0 | 14.1 | 0▼100% | 39▼37.1% |
| T. LemarCentral midfielder | Girona | 🇫🇷France | 30 | 3 | 1 | 13.4 | 24▲3933.3%↩ | 39▼13.2%↩ |
| GorosabelFull-back | Athletic Club | 🇪🇸Spain | 30 | 0 | 1 | 13 | 14▼60.5% | 39▼39.3% |
| JonnyCentre-back |  Alaves | 🇪🇸Spain | 32 | 0 | 0 | 12.9 | 29▲54.5%↩ | 40▲109%↩ |
| Luis RiojaCentral midfielder |  Valencia | 🇪🇸Spain | 32 | 3 | 6 | 17.5 | 46▲77% | 40▼21.4% |
| O. VlachodimosGoalkeeper | Sevilla | 🇬🇷Greece | 32 | 0 | 0 | 10.5 | 9▲93.2%↩ | 40▼8.5%↩ |
| Óscar ValentínDefensive midfielder | Rayo Vallecano | 🇪🇸Spain | 31 | 1 | 0 | 15.9 | 32▲65.8% | 40▼20.4% |
| Dani CárdenasGoalkeeper | Rayo Vallecano | 🇪🇸Spain | 29 | 0 | 0 | 14.6 | 3▼60.9% | 40▼26% |
| Héctor BellerínFull-back |  Real Betis | 🇪🇸Spain | 31 | 2 | 3 | 12 | 20▲235% | 40▼7.3% |
| Álex BerenguerCentral midfielder | Athletic Club | 🇪🇸Spain | 31 | 2 | 3 | 15.6 | 31▼25.1% | 41▼30.5% |
| Luiz FelipeCentre-back | Rayo Vallecano | 🇮🇹Italy | 29 | 0 | 0 | 14.9 | 11▲409.5%↩ | 41▼16%↩ |
| Kike BarjaWinger | Osasuna | 🇪🇸Spain | 29 | 2 | 2 | 15 | 12▲248.5% | 41▼21.8% |
| O. EjariaWinger | Oviedo | 🏴England | 28 | 0 | 0 | 16.5 | 0▼100%↩ | 42▼23.1%↩ |
| MouradCentre-forward |  Elche | 🇪🇸Spain | 28 | 0 | 0 | 16.6 | 0▼100% | 42▼27.2% |
| M. DiakhabyCentre-back | Valencia | 🇬🇳Guinea | 29 | 1 | 0 | 15.3 | 6▼41.1% | 42▼25.3% |
| Antonio SánchezCentral midfielder | Mallorca | 🇪🇸Spain | 29 | 0 | 0 | 15.3 | 9▼21% | 42▼28.3% |
| BruguiCentral midfielder |  Levante | 🇪🇸Spain | 29 | 1 | 1 | 15.3 | 13▼67.6% | 42▼29.5% |
| José GayàFull-back | Valencia | 🇪🇸Spain | 31 | 1 | 2 | 16.1 | 32▲28.6% | 42▼13.5% |
| V. MuriqiCentre-forward | Mallorca | 🇽🇰Kosovo | 32 | 23 | 1 | 18.9 | 77▲129.8% | 43▼8% |
| Álex SancrisCentre-forward | Getafe | 🇪🇸Spain | 29 | 0 | 1 | 15.6 | 4▼90.5%↩ | 43▼25.4%↩ |
| Cristian RiveroGoalkeeper | Valencia | 🇪🇸Spain | 28 | 0 | 0 | 17 | 0 | 43▼30% |
| H. MoldovanGoalkeeper | Oviedo | 🇷🇴Romania | 28 | 0 | 0 | 17.1 | 5▼84.5%↩ | 43▼25.6%↩ |
| C. PickelCentral midfielder |  Espanyol | 🇨🇭Switzerland | 29 | 1 | 0 | 15.7 | 11▼42.5%↩ | 43▼10.8%↩ |
| Marcos LlorenteFull-back | Atletico Madrid | 🇪🇸Spain | 31 | 0 | 4 | 32.7 | 40▼14.9% | 43▼26.2% |
| Álvaro FidalgoCentral midfielder | Real Betis | 🇪🇸Spain | 29 | 1 | 0 | 15.7 | 9▼14.7%↩ | 43▼20.6%↩ |
| A. MuminCentre-back | Rayo Vallecano | 🇬🇭Ghana | 28 | 0 | 0 | 17.3 | 1▼97.5% | 44▼38.1% |
| Unai LópezCentral midfielder | Rayo Vallecano | 🇪🇸Spain | 30 | 0 | 4 | 15 | 27▼11.7% | 44▼24% |
| GuevaraCentral midfielder | Alaves | 🇪🇸Spain | 29 | 1 | 1 | 15.9 | 13▼42.7% | 44▼28.2% |
| C. BenavídezDefensive midfielder | Alaves | 🇺🇾Uruguay | 28 | 0 | 0 | 17.4 | 4▼69.8% | 44▼29.1% |
| CatenaCentre-back | Osasuna | 🇪🇸Spain | 31 | 3 | 2 | 15.4 | 31▼16.2% | 44▼24% |
| Isi PalazónCentral midfielder | Rayo Vallecano | 🇪🇸Spain | 31 | 3 | 3 | 16.9 | 34▼9.3% | 44▼21.8% |
| G. Lo CelsoCentral midfielder | Real Betis | 🇦🇷Argentina | 30 | 2 | 3 | 14.7 | 24▼29.7% | 44▼25.5% |
| André SilvaCentre-forward | Elche | 🇵🇹Portugal | 30 | 10 | 0 | 20.3 | 37▲126.5%↩ | 45▼8.1%↩ |
| V. BirmančevićCentral midfielder | Getafe | 🇷🇸Serbia | 28 | 0 | 0 | 17.9 | 1▼95.9%↩ | 45▲26.8%↩ |
| Fernando CaleroCentre-back | Espanyol | 🇪🇸Spain | 30 | 0 | 0 | 17.4 | 32▲125.7% | 45▼7.2% |
| PedrazaFull-back |  Villarreal | 🇪🇸Spain | 30 | 1 | 3 | 25.2 | 24▲526.3% | 46▼9.9% |
| Junior FirpoFull-back | Real Betis | 🇪🇸Spain | 29 | 0 | 1 | 16.6 | 11▼81%↩ | 46▼25.9%↩ |
| Domingos DuarteCentre-back | Getafe | 🇵🇹Portugal | 31 | 1 | 1 | 20.4 | 41▲82.7% | 46▼6.3% |
| N. PépéWinger | Villarreal | 🇨🇮Côte d'Ivoire | 31 | 8 | 8 | 38 | 49▲80.2% | 46▼9.5% |
| Aitor RuibalCentral midfielder | Real Betis | 🇪🇸Spain | 30 | 4 | 2 | 21.1 | 38▲129.3% | 46▼18% |
| Borja MayoralCentre-forward | Getafe | 🇪🇸Spain | 29 | 4 | 1 | 17 | 18▼13.7% | 47▼21.3% |
| L. PétrotCentre-back | Elche | 🇫🇷France | 29 | 0 | 0 | 17 | 22▼39.4%↩ | 47▼24.4%↩ |
| Toni LatoFull-back | Mallorca | 🇪🇸Spain | 28 | 0 | 1 | 18.6 | 5▼48% | 47▼22.6% |
| Y. HerreraCentral midfielder |  Real Sociedad | 🇻🇪Venezuela | 28 | 0 | 0 | 31 | 5▼90%↩ | 47▼36.8%↩ |
| Álex RemiroGoalkeeper | Real Sociedad | 🇪🇸Spain | 31 | 0 | 0 | 23.3 | 3▼93.1% | 47▼20.5% |
| Miguel RubioCentre-back | Espanyol | 🇪🇸Spain | 28 | 1 | 0 | 18.7 | 5▼83.8%↩ | 47▼21.4%↩ |
| J. ToljanFull-back | Levante | 🇩🇪Germany | 31 | 1 | 4 | 19 | 38▼16.6%↩ | 47▼3.1%↩ |
| U. SadiqWinger | Valencia | 🇳🇬Nigeria | 29 | 4 | 2 | 17.2 | 20▲6.3% | 47▼20.3% |
| L. KrejčíCentre-back | Girona | 🇨🇿Czechia | 27 | 0 | 0 | 31.4 | 1▼97.8% | 47▼37.1% |
| G. DianganaWinger | Elche | 🏴England | 28 | 1 | 0 | 18.9 | 6▼67.7%↩ | 48▼17.2%↩ |
| F. GattoniCentre-back | Sevilla | 🇦🇷Argentina | 27 | 0 | 0 | 31.7 | 0▼100%↩ | 48▲10.6%↩ |
| S. ColombattoCentral midfielder | Oviedo | 🇦🇷Argentina | 29 | 0 | 1 | 17.5 | 22▼42.2% | 48▼15.2% |
| C. EjukeWinger | Sevilla | 🇳🇬Nigeria | 28 | 1 | 1 | 19.2 | 9▼28.1% | 48▼20.8% |
| Gonzalo VillarCentral midfielder | Elche | 🇪🇸Spain | 28 | 1 | 0 | 19.2 | 10▼60.3%↩ | 48▼14.5%↩ |
| Aihen MuñozFull-back | Real Sociedad | 🇪🇸Spain | 28 | 1 | 0 | 32.1 | 8▼60.3% | 48▼23.2% |
| R. NtekaAttacking midfielder | Rayo Vallecano | 🇫🇷France | 28 | 3 | 0 | 19.4 | 10▼48.7% | 49▼27% |
| A. SørlothCentre-forward | Atletico Madrid | 🇳🇴Norway | 30 | 13 | 0 | 41.4 | 45▼27.4% | 49▼23.5% |
| Edu ExpósitoCentral midfielder | Espanyol | 🇪🇸Spain | 30 | 1 | 6 | 24.1 | 44▲164.8% | 49▼3% |
| Adrià PedrosaDefensive midfielder | Elche | 🇪🇸Spain | 28 | 1 | 1 | 19.6 | 20▼43%↩ | 49▼28.6%↩ |
| Javi PuadoCentral midfielder | Espanyol | 🇪🇸Spain | 28 | 2 | 0 | 19.8 | 11▼80.6% | 50▼36.8% |
| Luis MillaCentral midfielder | Getafe | 🇪🇸Spain | 31 | 1 | 10 | 24.7 | 58▲38.6% | 50▼13.4% |
| Aarón EscandellGoalkeeper | Oviedo | 🇪🇸Spain | 30 | 0 | 1 | 16.6 | 23▼41% | 50▼7.6% |
| Oriol ReyCentral midfielder | Levante | 🇪🇸Spain | 28 | 0 | 1 | 20 | 14▼54% | 50▼19.9% |
| ZubeldiaCentre-back | Real Sociedad | 🇪🇸Spain | 29 | 0 | 1 | 30.5 | 15▼62.6% | 50▼22.3% |
| A. DanjumaWinger | Valencia | 🇳🇱Netherlands | 29 | 3 | 2 | 18.3 | 20▲8.7%↩ | 50▼16.4%↩ |
| Aleix FebasCentral midfielder | Elche | 🇪🇸Spain | 30 | 2 | 2 | 24.5 | 44▲42.4% | 50▼2.5% |
| Víctor GarcíaCentral midfielder | Levante | 🇪🇸Spain | 28 | 2 | 1 | 20 | 20▼30.6%↩ | 50▼25.9%↩ |
| M. ValjentCentre-back | Mallorca | 🇸🇰Slovakia | 30 | 0 | 0 | 16.7 | 25▼10.2% | 51▼18.7% |
| Diego CondeGoalkeeper | Villarreal | 🇪🇸Spain | 27 | 0 | 0 | 55.9 | 0▼100%↩ | 51▼30.2%↩ |
| D. Ćaleta-CarCentre-back | Real Sociedad | 🇭🇷Croatia | 29 | 1 | 0 | 30.8 | 16▼38.6%↩ | 51▼13.9%↩ |
| Robin Le NormandCentre-back | Atletico Madrid | 🇪🇸Spain | 29 | 1 | 1 | 31.7 | 31▼41.3% | 51▼24.3% |
| N. TenagliaCentre-back | Alaves | 🇦🇷Argentina | 30 | 2 | 0 | 19 | 35▼31.7% | 51▼16.6% |
| K. SiboCentral midfielder | Oviedo | 🇬🇭Ghana | 28 | 0 | 0 | 20.4 | 14▼46.4% | 51▼11.7% |
| J. FoythCentre-back | Villarreal | 🇦🇷Argentina | 28 | 0 | 0 | 34.2 | 14▼22.4% | 52▼23.6% |
| V. RosierCentral midfielder | Osasuna | 🇫🇷France | 29 | 1 | 1 | 20.6 | 34▼31%↩ | 52▼19.7%↩ |
| Marc RocaCentral midfielder | Real Betis | 🇪🇸Spain | 29 | 1 | 1 | 18.9 | 27▲97.1% | 52▼15.6% |
| Brais MéndezAttacking midfielder | Real Sociedad | 🇪🇸Spain | 29 | 6 | 2 | 31.5 | 29▲5.5% | 52▼19.2% |
| Pablo MaffeoFull-back | Mallorca | 🇪🇸Spain | 29 | 1 | 2 | 20.7 | 34▲6.2% | 52▼20.5% |
| J. LetáčekGoalkeeper | Getafe | 🇨🇿Czechia | 27 | 0 | 0 | 34.7 | 0 | 52 |
| F. de JongCentral midfielder | Barcelona | 🇳🇱Netherlands | 29 | 1 | 5 | 34.6 | 34▲55.5% | 53▼18.4% |
